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Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics
  • X. Li, X. Wang, +6 authors H. Xu
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 9 December 2013
TLDR
The development of a PI(3,5)P2-specific probe is reported, generated by the fusion of fluorescence tags to the tandem repeats of ML1N to activate late endosome and lysosome (LEL)-localized transient receptor potential Mucolipin 1 (TRPML1) channels. Expand
[Experts consensus on the management of the right heart function in critically ill patients].
To establish the experts consensus on the right heart function management in critically ill patients. The panel of consensus was composed of 30 experts in critical care medicine who are all membersExpand