• Publications
  • Influence
Design, expression and characterization of the hybrid antimicrobial peptide LHP7, connected by a flexible linker, against Staphylococcus and Streptococcus
Abstract The emergence of bacterial resistance to common antibiotics poses a threat to human health and has rekindled an interest in antimicrobial peptides (AMPs). LHP7, a novel hybrid AMP containingExpand
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Design, expression, and characterization of a novel targeted plectasin against methicillin-resistant Staphylococcus aureus
  • R. Mao, D. Teng, +5 authors J. Wang
  • Biology, Medicine
  • Applied Microbiology and Biotechnology
  • 12 March 2013
A novel specifically targeted antimicrobial peptide (STAMP) that was especially effective against methicillin-resistant Staphylococcus aureus (MRSA) was designed by fusing the AgrD1 pheromone to theExpand
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High expression of a plectasin-derived peptide NZ2114 in Pichia pastoris and its pharmacodynamics, postantibiotic and synergy against Staphylococcus aureus
NZ2114, a new variant of plectasin, was overexpressed in Pichia pastoris X-33 via pPICZαA for the first time. The total secreted protein of fermentation supernatant reached 2,390 mg/l (29 °C) andExpand
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The effects of intrauterine undernutrition on pancreas ghrelin and insulin expression in neonate rats.
Ghrelin has a correlation with insulin secretion, beta-cell development, and diabetes in crucial development period. The aim of this study was to compare the changes in plasma ghrelin, insulin, andExpand
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Metabolic syndrome in obese children born large for gestational age
ObjectiveThis study was to compare the prevalence of metabolic syndrome (MS) and insulin release in Chinese obese children born large-for-gestational age (LGA) with those bornExpand
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Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis
NZ17074 (N1), an arenicin-3 derivative isolated from the lugworm, has potent antibacterial activity and is cytotoxic. To reduce its cytotoxicity, seven N1 analogues with different structures wereExpand
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Evaluation of three read-depth based CNV detection tools using whole-exome sequencing data
BackgroundWhole exome sequencing (WES) has been widely accepted as a robust and cost-effective approach for clinical genetic testing of small sequence variants. Detection of copy number variantsExpand
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Novel pathogenic ACAN variants in non-syndromic short stature patients.
  • X. Hu, B. Gui, +17 authors Y. Shen
  • Medicine
  • Clinica chimica acta; international journal of…
  • 1 June 2017
BACKGROUND Pathogenic variants of ACAN have been reported to cause spondyloepiphyseal dysplasia Kimberley type, spondyloepimetaphyseal dysplasia, familial osteochondritis dissecans and idiopathicExpand
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Design and recombination expression of a novel plectasin-derived peptide MP1106 and its properties against Staphylococcus aureus
A novel antimicrobial peptide MP1106 was designed based on the parental peptide plectasin with four mutational sites and a high level of expression in Pichia pastoris X-33 via the pPICZαA plasmid wasExpand
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A Low-Complexity Massive MIMO Precoding Algorithm Based on Chebyshev Iteration
Precoding algorithm is used to transmit signals effectively and to reduce the interferences from other user terminals in the massive multiple-input-multiple-output (MIMO) systems. In order toExpand
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