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MicroRNAs are dynamically regulated in hypertrophic hearts, and miR‐199a is essential for the maintenance of cell size in cardiomyocytes
Cardiac hypertrophy, which is characterized by an increase in cell size and reactivation of fetal genes, occurs as an adaptive response to diverse forms of stress and often results in heart failureExpand
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Marijuana impairs growth in mid-gestation fetuses.
Marijuana (Cannabis sativa) is the most commonly used illicit drug by pregnant women, but information is limited about the effects of prenatal cannabis exposure on fetal development. The presentExpand
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Discrete opioid gene expression impairment in the human fetal brain associated with maternal marijuana use
Fetal development is a period sensitive to environmental influences such as maternal drug use. The most commonly used illicit drug by pregnant women is marijuana. The present study investigated theExpand
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Long noncoding RNAs in cancer‐immunity cycle
The imbalance of immune status in cancer microenvironment plays an important role in the development and progression of cancer. Immunotherapy based on this has become an important field of cancerExpand
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Combined therapy of allantoin, metronidazole, dexamethasone on the prevention of intra-abdominal adhesion in dogs and its quantitative analysis.
AIM To observe the preventive effects of combined therapy of AMD (allantoin, metronidazolem and dexamethasone in combination) on intra-abdominal adhesion in dogs. METHODS 20 dogs of both sexes wereExpand
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Chimeric-antigen receptor T (CAR-T) cell therapy for solid tumors: challenges and opportunities
Chimeric antigen receptor (CAR)-engineered T cells (CAR-T cells) have been shown to have unprecedented efficacy in B cell malignancies, most notably in B cell acute lymphoblastic leukemia (B-ALL)Expand
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Impact of a laparoscopic resection on the quality of life in rectal cancer patients: Results of 135 patients
PurposeTo investigate the impact of a laparoscopic resection on the quality of life in rectal cancer patients.MethodsThis study included 135 patients (laparoscopic resection [LR] 65 cases and openExpand
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MicroRNA-related single-nucleotide polymorphism of XPO5 is strongly correlated with the prognosis and chemotherapy response in advanced non-small-cell lung cancer patients
This study was performed to investigate if the microRNA-related single-nucleotide polymorphisms (miR-SNPs) of XPO5 gene predicted the prognosis and pathological features of advanced non-small-cellExpand
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Leptin protects cardiomyocytes from serum‐deprivation‐induced apoptosis by increasing anti‐oxidant defence
  • J. Zheng, J. Fang, +6 authors L. Lin
  • Biology, Medicine
  • Clinical and experimental pharmacology…
  • 1 October 2010
1. Leptin, an important adipose‐derived hormone, can be associated with cardiac pathophysiology; however, the role of leptin in cardiomyocyte apoptosis is poorly understood. The present studyExpand
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MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease.
AIM To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model. METHODS QuantitativeExpand
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