• Publications
  • Influence
The first asymmetric total synthesis of several 3,4-dihydroxy-2,2-dimethyl-chroman derivatives
Abstract The stereoisomers of 3,4-dihydroxy-6-methoxy-2,2-dimethyl-chroman 1a–c and 3,4,7-trihydroxy-6-acetyl-2,2-dimethyl-chroman 2a–c were conveniently prepared for the first time via a synthesisExpand
  • 23
  • 2
Concise formal synthesis of (+)-neopeltolide.
A concise formal synthesis of (+)-neopeltolide (1) has been accomplished. The synthesis demonstrated high atom efficiency employing only one step of functional group protection. Key steps involvedExpand
  • 52
  • 1
Designing new chiral ketone catalysts. Asymmetric epoxidation of cis-olefins and terminal olefins.
This paper describes a new class of chiral oxazolidinone ketone catalyst for asymmetric epoxidation. High ee values have been obtained for a number of cyclic and acyclic cis-olefins. The epoxidationExpand
  • 77
  • 1
A one-step method to produce graphene–Fe3O4 composites and their excellent catalytic activities for three-component coupling of aldehyde, alkyne and amine
The construction of reduced graphene oxide or graphene oxide (GO) with magnetic nanoparticles has gained more and more attention due to its promising and wide applications in catalysis, photoelectricExpand
  • 75
Enantioselective epoxidation of terminal olefins by chiral dioxirane.
[see reaction]. This paper describes an enantioselective epoxidation of terminal olefins using chiral ketone 3 as catalyst and Oxone as oxidant. Up to 85% ee has been obtained.
  • 76
Efficient and regioselective one-pot synthesis of 3-substituted and 3,5-disubstituted isoxazoles.
A series of 3-substituted and 3,5-disubstituted isoxazoles have been efficiently synthesized in moderate to excellent yields by the reaction of N-hydroxyl-4-toluenesulfonamide withExpand
  • 83
Application of a domino Friedel-Crafts acylation/alkylation reaction to the formal syntheses of (+/-)-taiwaniaquinol B and (+/-)-dichroanone.
An efficient acid-promoted domino Friedel-Crafts (FC) acylation/alkylation reaction has been developed for the construction of the core 6,5,6-ABC tricyclic skeleton of taiwaniaquinoids. The formalExpand
  • 38
N-heterocyclic carbene catalyzed nucleophilic substitution reaction for construction of benzopyrones and benzofuranones.
N-Heterocyclic carbene as an efficient organic catalyst was employed to catalyze an intramolecular nucleophilic substitution reaction. When R(2) was a phenyl group, the cyclization process underwentExpand
  • 53
N-heterocyclic carbene (NHC)-catalyzed/Lewis acid mediated conjugate umpolung of alkynyl aldehydes for the synthesis of butenolides: a formal [3+2] annulation.
Reverse to success! A new formal [3+2] annulation reaction combining alkynyl aldehydes and β,γ-unsaturated α-ketoesters has been disclosed by using a NHC-catalyzed/Lewis acid mediated strategy. ThisExpand
  • 46