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Effects of uric acid-lowering therapy on the progression of chronic kidney disease: a systematic review and meta-analysis
Abstract Objectives: Whether uric acid levels were associated with the progression of chronic kidney disease (CKD) remained controversial. This meta-analysis was aimed to assess the effect of… Expand
A New Criterion for Pediatric AKI Based on the Reference Change Value of Serum Creatinine.
- X. Xu, S. Nie, +29 authors F. Hou
- Journal of the American Society of Nephrology…
- 1 September 2018
BACKGROUND Current definitions of AKI do not take into account serum creatinine's high variability in children. METHODS We analyzed data from 156,075 hospitalized children with at least two… Expand
Genetic variations in the vitamin-D receptor (VDR) gene in preeclampsia patients in the Chinese Han population
Previous studies have indicated that vitamin D deficiency is linked to a risk of preeclampsia (PE). The aim of our study was to investigate the association between genetic variations in the vitamin-D… Expand
Genetic spectrum of renal disease for 1001 Chinese children based on a multicenter registration system
To explore the approaches and diagnostic yield of genetic testing for renal disease in children, we describe the genotype and phenotype of the national cohort of children with renal disease from 13… Expand
Acute Kidney Injury among Hospitalized Children in China.
- X. Xu, S. Nie, +26 authors F. Hou
- Clinical journal of the American Society of…
- 7 December 2018
BACKGROUND AND OBJECTIVES High-quality epidemiologic data on AKI in children are particularly lacking in developing countries. This study aimed to assess the epidemiology and clinical correlates of… Expand
Calreticulin is a microbial-binding molecule with phagocytosis-enhancing capacity.
Calreticulin (CRT) is a highly conserved calcium-binding protein mainly involved in directing proper conformation of proteins and controlling calcium level. Accumulating data also show that CRT is… Expand
Detection and characterization of phenoloxidase in the freshwater planarian Dugesia japonica.
- Q. Pang, X. Liu, +6 authors Huanhuan Sun
- Biology, Medicine
- Comparative biochemistry and physiology. Part B…
- 1 September 2010
Freshwater planarians have traditionally been favored animal models in regenerative and developmental biology. Little is known about the immunological research in these animals. Here, we provide… Expand
Gut microbiota dysbiosis is associated with Henoch‐Schönlein Purpura in children
- Xingcui Wang, L. Zhang, +6 authors Z. Gai
- Biology, Medicine
- International immunopharmacology
- 8 March 2018
Background: Alterations in the intestinal microbiota have been associated with the development of allergic diseases, such as asthma and food allergies. However, there is no report detailing the role… Expand
Genetic variations in IL1A and IL1RN are associated with the risk of preeclampsia in Chinese Han population
Preeclampsia (PE) is an excessive systemic inflammation response with dysfunction of endothelial. Our study was to investigate the association between genetic variations in IL-1 and the… Expand
Humoral immune responses of amphioxus Branchiostoma belcheri to challenge with Escherichia coli.
Humoral parameters of amphioxus Branchiostoma belcheri, including lysozyme, antimicrobial activity, microbial agglutinin and haemagglutinins were measured before and after challenge with Escherichia… Expand