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Novel Reassortant Highly Pathogenic H5N2 Avian Influenza Viruses in Poultry in China
There has been multiple evidence that domestic poultry may act as a vessel for the generation of novel influenza A viruses. In this study, we have analyzed the evolution and pathogenicity of 4 H5N2… Expand
Genetic diversity of avian infectious bronchitis coronavirus strains isolated in China between 1995 and 2004
Summary.Twenty-six avian infectious bronchitis (IB) viruses (IBV) were isolated from outbreaks in chickens in China between 1995 and 2004. They were characterized by comparison with twenty-six… Expand
Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China.
One H5N8 and three H5N5 highly pathogenic avian influenza (HPAI) viruses which derived their HA genes from the Asian H5N1 lineage were isolated from poultry during 2009-2010 in mainland China.… Expand
Novel Reassortant Highly Pathogenic Avian Influenza (H5N5) Viruses in Domestic Ducks, China
In China, domestic ducks and wild birds often share the same water, in which influenza viruses replicate preferentially. Isolation of 2 novel reassortant highly pathogenic avian influenza (H5N5)… Expand
Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009–2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined… Expand
Characterization of clade 126.96.36.199 highly pathogenic H5 avian influenza viruses in ducks and chickens.
Worldwide dissemination of reassortant variants of H5 clade 188.8.131.52 highly pathogenic avian influenza (HPAI) viruses has posed a great threat to the poultry industry. Here, we systematically… Expand
Molecular Basis for Broad Neuraminidase Immunity: Conserved Epitopes in Seasonal and Pandemic H1N1 as Well as H5N1 Influenza Viruses
ABSTRACT Influenza A viruses, including H1N1 and H5N1 subtypes, pose a serious threat to public health. Neuraminidase (NA)-related immunity contributes to protection against influenza virus… Expand
Epidemiology, Evolution, and Pathogenesis of H7N9 Influenza Viruses in Five Epidemic Waves since 2013 in China.
H7N9 influenza viruses were first isolated in 2013 and continue to cause human infections. H7N9 infections represent an ongoing public health threat that has resulted in 1344 cases with 511 deaths as… Expand
Phylogenetic Analysis of the Hemagglutinin Genes of Twenty-Six Avian Influenza Viruses of Subtype H9N2 Isolated from Chickens in China During 1996–2001
SUMMARY. The complete coding region of hemagglutinin genes from 26 influenza A viruses of H9N2 subtype isolated from chicken flocks in China during 1996–2001 was amplified and sequenced. Sequence… Expand
PA-X Decreases the Pathogenicity of Highly Pathogenic H5N1 Influenza A Virus in Avian Species by Inhibiting Virus Replication and Host Response
ABSTRACT PA-X is a newly discovered protein that decreases the virulence of the 1918 H1N1 virus in a mouse model. However, the role of PA-X in the pathogenesis of highly pathogenic avian influenza… Expand