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First-line erlotinib versus gemcitabine/cisplatin in patients with advanced EGFR mutation-positive non-small-cell lung cancer: analyses from the phase III, randomized, open-label, ENSURE study.
- Y. Wu, C. Zhou, +19 authors Y. Zuo
- Annals of oncology : official journal of the…
- 1 September 2015
BACKGROUND The phase III, randomized, open-label ENSURE study (NCT01342965) evaluated first-line erlotinib versus gemcitabine/cisplatin (GP) in patients from China, Malaysia and the Philippines with… Expand
Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus.
In order to study the mechanism of neural patterning in Xenopus, we used subtractive cloning to isolate genes activated early during this process. One gene isolated was opl, (odd-paired-like) that… Expand
Nonsyndromic Hearing Loss: An Analysis of Audiograms
We examined features of the audiograms of 136 individuals, from 28 families, affected by nonsyndromic genetic hearing loss. There were 83 (12 families) with autosomal dominant (AD) loss, 50 (15… Expand
Efficacy and safety of ginsenoside‐Rd for acute ischaemic stroke: a randomized, double‐blind, placebo‐controlled, phase II multicenter trial
Background and purpose: Ginsenoside‐Rd is a selective competitive Ca2+ receptor antagonist. A phase II randomized, double‐blind, placebo‐controlled, multicenter study was conducted to examine the… Expand
Epidemiological and genetic studies of congenital profound deafness in the general population of Sichuan, China.
People with congenital profound deafness (CPD) were surveyed in the general population of Sichuan. The prevalence was 0.082% (104/126, 876) of the general population, male 0.086%, female 0.078%.… Expand
Association of asymptomatic oral candidal carriage, oral candidiasis and CD4 lymphocyte count in HIV-positive patients in China.
OBJECTIVES To compare the prevalence of asymptomatic oral candidal carriage in healthy volunteers with human immunodeficiency virus (HIV)-positive patients in China, as well as to investigate the… Expand
Prevalence and aetiology of profound deafness in the general population of Sichuan, China.
People with profound deafness were surveyed in the general population of Sichuan. The results showed that the overall prevalence in Sichuan was 0.186 per cent (236/126,876) of the general population,… Expand
The clinical spectrum of female epilepsy patients with PCDH19 mutations in a Chinese population
Mutations in PCDH19, which encodes protocadherin 19, have been identified in epilepsy, mainly in affected females. We summarized the clinical spectrum of female epilepsy patients with PCDH19… Expand
Long non-coding RNA TRPM2-AS as a potential biomarker for hepatocellular carcinoma
BackgroundThere is increasing evidence that long non-coding RNAs are involved in hepatocellular carcinoma (HCC) tumorigenesis. The expression level of TRPM2-AS in HCC and its clinical association… Expand
Interleukin‐21 induces migration and invasion of fibroblast‐like synoviocytes from patients with rheumatoid arthritis
- R. Xing, Y. Jin, +5 authors J. Zhao
- Chemistry, Medicine
- Clinical and experimental immunology
- 1 May 2016
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial fibroblast hyperplasia and bone erosion. Fibroblast‐like synoviocytes (FLS) play a pivotal role in RA… Expand