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The determinants of Chinese outward foreign direct investment
This study investigates the determinants of Chinese outward direct investment (ODI) and the extent to which three special explanations (capital market imperfections, special ownership advantages andExpand
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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer.
The murine Pten prostate cancer model described in this study recapitulates the disease progression seen in humans: initiation of prostate cancer with prostatic intraepithelial neoplasia (PIN),Expand
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Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
Erythropoietin (EPO) is the principal growth factor regulating the production of circulating erythrocytes. We introduced null mutations into both Epo and the EPO receptor (EpoR) gene. BothExpand
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Sensory but not motor neuron deficits in mice lacking NT4 and BDNF
NEUROTROPHINS play important roles in neuronal survival during vertebrate development1–3. Neurotrophin-4 (NT4), alone or in combination with brain-derived neurotrophic factor (BDNF), has beenExpand
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Network model of survival signaling in large granular lymphocyte leukemia
T cell large granular lymphocyte (T-LGL) leukemia features a clonal expansion of antigen-primed, competent, cytotoxic T lymphocytes (CTL). To systematically understand signaling components thatExpand
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Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review
Graphical abstract
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Pten Deletion in Adult Neural Stem/Progenitor Cells Enhances Constitutive Neurogenesis
Here we show that conditional deletion of Pten in a subpopulation of adult neural stem cells in the subependymal zone (SEZ) leads to persistently enhanced neural stem cell self-renewal without signExpand
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PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry.
Previous studies have demonstrated that a small subpopulation of brain tumor cells share key characteristics with neural stem/progenitor cells in terms of phenotype and behavior. These findingsExpand
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Elevated Phosphatidylinositol 3,4,5-Trisphosphate in Glia Triggers Cell-Autonomous Membrane Wrapping and Myelination
In the developing nervous system, constitutive activation of the AKT/mTOR (mammalian target of rapamycin) pathway in myelinating glial cells is associated with hypermyelination of the brain, but isExpand
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CD28 and CD3 have complementary roles in T-cell traction forces
Significance Cells have the remarkable ability to sense the mechanical properties of the extracellular environment. This has been developed primarily in the context of cell interaction withExpand
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