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Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation
Heparan sulfate proteoglycans (HSPG) have been implicated in regulating the signalling activities of secreted morphogen molecules including Wingless (Wg), Hedgehog (Hh) and Decapentaplegic (Dpp).Expand
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pygopus Encodes a nuclear protein essential for wingless/Wnt signaling.
The Wingless (Wg)/Wnt signal transduction pathway regulates many developmental processes through a complex of Armadillo(Arm)/beta-catenin and the HMG-box transcription factors of the Tcf family. WeExpand
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Mutational Analysis Establishes a Critical Role for the N Terminus of Fragile X Mental Retardation Protein FMRP
Fragile X syndrome is the most common form of heritable mental retardation caused by the loss of function of the fragile X mental retardation protein FMRP. FMRP is a multidomain, RNA-binding proteinExpand
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Methoprene-tolerant (Met) and Krüpple-homologue 1 (Kr-h1) are required for ovariole development and egg maturation in the brown plant hopper
The brown plant hopper is one of the most destructive known pests of rice. We studied the roles of the JH receptor Met and the downstream transcription factor Kr-h1 in ovariole development and eggExpand
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Distinct Roles of Met and Interacting Proteins on the Expressions of takeout Family Genes in Brown Planthopper
The takeout family genes encode relatively small proteins that are related to olfaction and are regulated by juvenile hormone (JH). The takeout genes modulate various physiological processes, such asExpand
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Transcriptome and expression profiling analysis link patterns of gene expression to antennal responses in Spodoptera litura
AbstractBackgroundThe study of olfaction is key to understanding the interaction of insects with their environment and provides opportunities to develop novel Expand
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Drosophila CG10527 mutants are resistant to juvenile hormone and its analog methoprene.
Juvenile hormone (JH) is critical for development, metamorphosis, and reproduction in insects. While the physiological importance of JH has been appreciated for decades, its biosynthetic pathway andExpand
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Ecological Trade-offs between Migration and Reproduction Are Mediated by the Nutrition-Sensitive Insulin-Signaling Pathway
Crowding and changes in food availability are two critical environmental conditions that impact an animal's trajectory toward either migration or reproduction. Many insects facing this challenge haveExpand
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Host quality induces phenotypic plasticity in a wing polyphenic insect
Significance Variation in food nutrient content and density are key ecological factors linked to the expression of condition-dependent, adaptive phenotypes such as wing polyphenisms. There is veryExpand
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Role of Broad-Complex (Br) and Krüppel homolog 1 (Kr-h1) in the Ovary Development of Nilaparvata lugens
Ovarian development plays an important role in the life history of insects and is crucial for control of the insect population. The metamorphosis of an insect is precisely regulated by theExpand
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