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RESEARCH ADVANCE OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A SYNTHASE IN PLANT ISOPRENOID BIOSYNTHESIS
Terpenoids are synthesized in plants via the mevalonate (MVA) and the methylerythritol phosphate (MEP) pathways, with isopentenyl diphosphate (IPP) as the main intermediate metabolite. 3… Expand
Deletion of the epigenetic regulator GcnE in Aspergillus niger FGSC A1279 activates the production of multiple polyketide metabolites.
Epigenetic modification is an important regulatory mechanism in the biosynthesis of secondary metabolites in Aspergillus species, which have been considered to be the treasure trove of new bioactive… Expand
Profiling of secondary metabolite gene clusters regulated by LaeA in Aspergillus niger FGSC A1279 based on genome sequencing and transcriptome analysis.
- B. Wang, Yangyong Lv, X. Li, Y. Lin, H. Deng, L. Pan
- Biology, Medicine
- Research in microbiology
- 1 October 2017
The global regulator LaeA controls the production of many fungal secondary metabolites, possibly via chromatin remodeling. Here we aimed to survey the secondary metabolite profile regulated by LaeA… Expand
Mechanistic and conformational studies on the interaction of anesthetic sevoflurane with human serum albumin by multispectroscopic methods
Abstract To know the interaction of sevoflurane with human serum albumin (HSA), techniques of different spectroscopies were used. Steady state fluorescence suggested a static type for sevoflurane–HSA… Expand
Fermentative hydrogen production with peanut shell as supplementary substrate: effects of initial substrate, pH and inoculation proportion.
Abstract Peanut shell (PS) was the first-time used as a supplementary substrate for fermentative hydrogen production, and the effects of initial substrate concentration, pH and inoculum proportion… Expand
Massilia neuiana sp. nov., isolated from wet soil.
- X. Zhao, X. Li, +4 authors X. Hu
- Biology, Medicine
- International journal of systematic and…
- 16 October 2017
A novel aerobic, Gram-stain-negative, rod-shaped, motile bacterium, strain PTW21T, was isolated from wet soil. 16S rRNA gene sequence phylogenetic analysis of strain PTW21T revealed an affiliation to… Expand
Enhancement of fermentative H2 production with peanut shell as supplementary substrate: Effects of acidification and buffer effect.
For bio-H2 fermentation, the progress and H2 yield were significantly affected by culture pH. Our previous research found peanut shell powder (PSP, as supplementary substrate) having a buffer effect… Expand
The Histone Deacetylases HosA and HdaA Affect the Phenotype and Transcriptomic and Metabolic Profiles of Aspergillus niger
Histone acetylation is an important modification for the regulation of chromatin accessibility and is controlled by two kinds of histone-modifying enzymes: histone acetyltransferases (HATs) and… Expand
Characterization and phylogenetic analysis of the mitochondrial genome of Hemitripterus villosus
Abstract Hemitripterus villosus is an important economic fish. With the completion of H. villosus mitochondrial genome sequencing, the full-length mitochondrial genome of H. villosus was assembled… Expand
Profiling of chromatin accessibility across Aspergillus species and identification of transcription factor binding sites in the Aspergillus genome using filamentous fungi ATAC-seq
To identify cis-regulatory elements (CREs) and motifs of TF binding is an important step in understanding the regulatory functions of TF binding and gene expression. The lack of experimentally… Expand