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PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma
Glioblastoma multiform (GBM) is the most common malignant glioma of all the brain tumors and currently effective treatment options are still lacking. GBM is frequently accompanied with overexpressionExpand
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MALAT1 induced migration and invasion of human breast cancer cells by competitively binding miR-1 with cdc42.
Competitive endogenous messenger RNAs (ceRNAs) affect other RNAs transcription through competitively binding common microRNAs (miRNAs). In this study we identified long non-coding RNA (lncRNA) MALAT1Expand
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Occurrence, removal, and fate of progestogens, androgens, estrogens, and phenols in six sewage treatment plants around Dianchi Lake in China
  • Bin Huang, X. Li, +6 authors X. Pan
  • Chemistry, Medicine
  • Environmental Science and Pollution Research
  • 1 July 2014
The occurrence and behavior of endocrine disrupting chemicals (EDCs) in sewage treatment plants (STPs), especially estrogens and phenols, have been closely concerned in previous studies. However, theExpand
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STARD13-correlated ceRNA network inhibits EMT and metastasis of breast cancer
Competing endogenous RNAs (ceRNAs) network has been correlated with the initiation and development of cancer. Here, we identify CDH5, HOXD1, and HOXD10 as putative STARD13 ceRNAs and they displayExpand
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Estimating the repeat structure and length of DNA sequences using L-tuples.
In shotgun sequencing projects, the genome or BAC length is not always known. We approach estimating genome length by first estimating the repeat structure of the genome or BAC, sometimes of interestExpand
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The 3′UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1
Pseudogenes are now known to regulate their protein-coding counterparts. Additionally, disturbances of 3′UTRs could increase the risk of cancer susceptibility by acting as modulators of geneExpand
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Loss of Caveolin-1 Impairs Retinal Function Due to Disturbance of Subretinal Microenvironment*
Background: Caveolin-1 is widely expressed in the retina and is linked to ocular disease. Results: Loss of caveolin-1 results in defective retinal function and ion homeostasis that is notExpand
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SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation.
Transcriptional and chromatin regulations mediate the liver response to nutrient availability. The role of chromatin factors involved in hormonal regulation in response to fasting is not fullyExpand
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miR‐125a‐3p inhibits ERα transactivation and overrides tamoxifen resistance by targeting CDK3 in estrogen receptor–positive breast cancer
Tamoxifen (TAM) is a major adjuvant therapy for patients who are diagnosed with estrogen receptor‐α(ER)–positive breast cancer; however, TAM resistance occurs often during treatment and theExpand
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STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling
BackgroundTargeting cancer stem cells is critical for suppressing cancer progression and recurrence. Finding novel markers or related pathways could help eradicate or diagnose cancer inExpand
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