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Morphometric and metabolic indices of disuse in muscles of hibernating ground squirrels.
1. Morphological, biochemical and metabolic characteristics of hindlimb muscles from summer-active (SA), winter-active (WA) and hibernating (H) golden-mantled ground squirrels (SpermophilusExpand
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Disuse Atrophy of Skeletal Muscle: Animal Models
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Skeletal muscle atrophy in response to 14 days of weightlessness: vastus medialis.
The vastus medialis (VM) from rats after 14 days of microgravity on COSMOS 2044 (F) was compared with VM from tail-suspended hindlimb-unloaded rats (T) and ground controls, including vivarium (V),Expand
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Rat cardiovascular responses to whole body suspension: head-down and non-head-down tilt.
The rat whole body suspension technique mimics responses seen during exposure to microgravity and was evaluated as a model for cardiovascular responses with two series of experiments. In one series,Expand
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Model for antiorthostatic hypokinesia: head-down tilt effects on water and salt excretion.
Water and electrolyte excretion was investigated in antiorthostatic hypokinetic and orthostatic hypokinetic and control rats in metabolic cages. Significant (t test, P < 0.05), diuresis, natriuresis,Expand
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Blood gases in hibernating and active ground squirrels: HbO2 affinity at 6 and 38 C.
Venous and arterial blood gases in hibernating and normothermic ground squirrels, showing venous oxygen and carbon dioxide partial pressures reduction in hibernation
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A model for hypokinesia: effects on muscle atrophy in the rat.
Hypokinesia in the hindlimbs of rats were induced by suspension; a newly developed harness system was used. The animal was able to use its forelimbs to maneuver, within a 140 degrees arc, to obtainExpand
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A suspension model for hypokinetic/hypodynamic and antiorthostatic responses in the mouse.
Hypokinetic/hypodynamic and antiorthostatic responses to weightlessness and bedrest were simulated in mice using a suspension technique. Animals were suspended for 1 or 2 weeks in an antiorthostaticExpand
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Survival of whole-body-irradiated hibernating and active ground squirrels; Citellus tridecemlineatus.
Active and hibernating ground squirrels, Citellus tridecemlineatus, were exposed to whole-body ${}^{60}{\rm C}$ gamma rays at dose rates of 190 to 175 rads per minute over a range of doses of 900 toExpand
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Blood gases in hamsters during hypothermia by exposure to He-O2 mixture and cold.
Blood oxygen, carbon dioxide and pN during hypothermia induced by He-oxygen mixture and cold exposure in hamsters, comparing with hibernation state
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