• Publications
  • Influence
Interprotofilament interactions between Alzheimer's Aβ1–42 peptides in amyloid fibrils revealed by cryoEM
  • R. Zhang, X. Hu, +5 authors J. Lee
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences
  • 24 March 2009
Alzheimer's disease is a neurodegenerative disorder characterized by the accumulation of amyloid plaques in the brain. This amyloid primarily contains amyloid-β (Aβ), a 39- to 43-aa peptide derivedExpand
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Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals
Agrobacterium tumefaciens is a broad host range plant pathogen that combinatorially recognizes diverse host molecules including phenolics, low pH, and aldose monosaccharides to activate itsExpand
  • 39
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High-resolution design of a protein loop
Despite having irregular structure, protein loops often adopt specific conformations that are critical to protein function. Most studies in de novo protein design have focused on creating proteinsExpand
  • 108
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A comprehensive plan for treating the major polluted regions of Lake Taihu, China
The Lake Taihu drainage basin is an economically developed area, containing almost the highest population density and most populous cities and towns in China. It is also among the largest lake basinsExpand
  • 28
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Protein design simulations suggest that side-chain conformational entropy is not a strong determinant of amino acid environmental preferences.
Loss of side-chain conformational entropy is an important force opposing protein folding and the relative preferences of the amino acids for being buried or solvent exposed may be partiallyExpand
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Studies on the Growth Characteristics of Microcystis aeruginosa
The effect of pH,disturbance and nutrients on the growth of Microcystis aeruginosa was studied.It is shown that for the growth of Microcystis aeruginosa,the most adaptive pH is 8.5~9.5 and its growthExpand
  • 12
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Control concept and countermeasures for shallow lakes’ eutrophication in China
Research on lake eutrophication in China began in the early 1970s, and many lakes in China are now known to be in meso-eutrophic status. Lake eutrophication has been showing a rapidly increasingExpand
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Flexible and Salt Resistant Janus Absorbers by Electrospinning for Stable and Efficient Solar Desalination
DOI: 10.1002/aenm.201702884 during desalination process and block the channels for vapor escape, resulting in the reduction of energy transfer efficiency, pure water yield, and unstable performance.Expand
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Spatiotemporal Distribution of Eutrophication in Lake Tai as Affected by Wind
One common hypothesis is that wind can affect concentrations of nutrients (i.e., nitrogen and phosphorus) and chlorophyll-a (Chl-a) in shallow lakes. However, the tests of this hypothesis have yet toExpand
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A dualistic water cycle system dynamic model for sustainable water resource management through progressive operational scenario analysis
A reliable system simulation of the reciprocal mechanism between water resource utilization and dualistic water cycle is essential to the basin water resource sustainability management. In thisExpand
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