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Molecular identification of adulteration in mutton based on mitochondrial 16S rRNA gene
  • Jia Xu, W. Zhao, +8 authors T. Zhong
  • Biology, Medicine
  • Mitochondrial DNA. Part A, DNA mapping…
  • 2 January 2016
TLDR
This multi-PCR assay successfully discriminated the double-, triple-, quadruple-, and quintuple-mixtures containing variant counterparts, which will be particularly useful in the detection of mutton adulteration in processed foods further. Expand
The 19q13 KRAB Zinc-finger protein ZFP82 suppresses the growth and invasion of esophageal carcinoma cells through inhibiting NF-κB transcription and inducing apoptosis.
TLDR
ZFP82 is a tumor suppressor and is disrupted by promoter CpG methylation during esophageal carcinogenesis and is correlated with age, tumor stage and outcome. Expand
The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
TLDR
It is suggested that DACT2 promoter methylation is a potential epigenetic biomarker for the detection and chemotherapy guidance of NPC, while it inhibits NPC cell proliferation and metastasis via suppressing β-catenin/Cdc25c signaling. Expand
ADAMTS9 is Silenced by Epigenetic Disruption in Colorectal Cancer and Inhibits Cell Growth and Metastasis by Regulating Akt/p53 Signaling
TLDR
Exogenous expression of ADAMTS9 in colorectal cancer cell lines inhibited cell proliferation and migration through the regulation of cell cycle and apoptosis and prevented the activation of Akt, and its downstream targets in colOREctalcancer cell lines. Expand
Electron-transfer-dominated non-radical activation of peroxydisulfate for efficient removal of chlorophenol contaminants by one-pot synthesized nitrogen and sulfur codoped mesoporous carbon.
TLDR
Results of in-situ Raman and electrochemical tests show that the surface-confined and activated PDS complex (carbon-PDS*) and continuous electron transfer from co-adsorbed 4-CP are mainly responsible for the oxidative degradation of chlorophenols, and provides in-depth knowledge of carbon-driven nonradical process for PDS activation and contaminants remediation. Expand
TET1 exerts its anti-tumor functions via demethylating DACT2 and SFRP2 to antagonize Wnt/β-catenin signaling pathway in nasopharyngeal carcinoma cells
TLDR
It is concluded that TET1 exerts its anti-tumor functions in NPC cells by suppressing Wnt/β-catenin signaling via demethylation of Wnt antagonists (DACT2 and SFRP2). Expand
Lipid Profiling, Particle Size Determination, and in Vitro Simulated Gastrointestinal Lipolysis of Mature Human Milk and Infant Formula.
TLDR
Higher gastrointestinal lipolysis rate of mature human milk fat as compared to infant formula fats might be due to the presence of MFGM interfacial layer (phospholipids) surrounding the fat droplets which govern lipase activity on lipid droplets. Expand
KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer
TLDR
The findings of this study suggest that ZNF382 functions as a tumor suppressor in GC cells, but is frequently methylated in both GC cell lines and primary gastric tumors. Expand
Inactivation of ADAMTS18 by aberrant promoter hypermethylation contribute to lung cancer progression
TLDR
The results demonstrated that the tumor suppressor gene ADAMTS18 was downregulated in lung cancer by promoter CpG methylation, and it promoted sensitivity to cisplatin via EGFR/AKT signaling. Expand
The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism
TLDR
The results for the first time suggest that CYGB suppresses breast cancer through inhibiting glucose metabolism, which could be exploited for breast cancer prevention and therapy. Expand
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