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Complete genome sequence of Lactobacillus plantarum JDM1.
TLDR
The genome of Lactobacillus plantarum JDM1, which is a Chinese commercial LAB with several probiotic functions, is sequenced using a GS 20 system to ensure safety and stability. Expand
High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans
TLDR
This systematic analysis provides not only comprehensive information of high-coverage protein expression and multiple modifications in prokaryotes but also a view suggesting that the evolutionarily primitive L. interrogans shares significant similarities in protein modification systems with eukaryotes. Expand
Bacterial, archaeal and eukaryotic diversity in Arctic sediment as revealed by 16S rRNA and 18S rRNA gene clone libraries analysis
TLDR
It is suggested that Arctic sediment as a unique habitat may contain substantial microbial diversity and novel species will be discovered. Expand
Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601
TLDR
Altered expression or mutations in critical genes, such as those encoding a Ser/Thr kinase, carbon-starvation protein CstA, glutamine synthetase, GTP-binding protein BipA, ribonucleotide-diphosphate reductase and phosphate transporter, and alterations in the translational profile of lipoproteins or outer membrane proteins are likely to account for the virulence attenuation in strain IPAV. Expand
Genome-wide transcriptional analysis of temperature shift in L. interrogans serovar lai strain 56601
TLDR
Microarray analyses demonstrated that L. interrogans responds globally to temperature alteration and delineate the spectrum of temperature-regulated gene expression in an important human pathogen and provide many new insights into its pathogenesis. Expand
Reduced Staphylococcus aureus biofilm formation in the presence of chitosan-coated iron oxide nanoparticles
TLDR
In vitro studies revealed that chitosan-coated iron oxide nanoparticles inhibited biofilm formation in polystyrene plates and future studies should be performed to study these nanoparticles for anti-infective use. Expand
Immunoproteomic Analysis of Human Serological Antibody Responses to Vaccination with Whole-Cell Pertussis Vaccine (WCV)
TLDR
This study is the first time that the repertoire of human serum antibody responses against WCV was comprehensively investigated, and a small number of previously unidentified antigens of WCV were also found by means of the classic immunoproteomic strategy. Expand
Biocompatibility of chitosan-coated iron oxide nanoparticles with osteoblast cells
TLDR
Chitosan-coated iron oxide nanoparticles enhanced osteoblast proliferation, decreased cell membrane damage, and promoted cell differentiation, as indicated by an increase in alkaline phosphatase and extracellular calcium deposition. Expand
Antimicrobial Resistance and Molecular Epidemiology of Escherichia coli Causing Bloodstream Infections in Three Hospitals in Shanghai, China
TLDR
A retrospective multicenter study on antimicrobial resistance and phylogenetic background of clinical E. coli isolates recovered from bloodstream in three hospitals in Shanghai showed no evidence suggesting a spread of these antimicrobial resistant isolates in the three hospitals. Expand
Isolation and Characterization of Two Novel Plasmids from Pathogenic Leptospira interrogans Serogroup Canicola Serovar Canicola Strain Gui44
TLDR
Quantitative PCR and next-generation sequencing confirms the presence of two separate circular plasmids in serovar Canicola strain Gui44 and provides a new understanding of genomic organization, adaptation, evolution and pathogenesis of Leptospira, which will aid in the development of in vivo genetic manipulation systems in pathogenic Leptonospira species. Expand
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