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Pre-Pregnancy Body Mass Index in Relation to Infant Birth Weight and Offspring Overweight/Obesity: A Systematic Review and Meta-Analysis
Background Overweight/obesity in women of childbearing age is a serious public-health problem. In China, the incidence of maternal overweight/obesity has been increasing. However, there is not a… Expand
Characterization of Serum MicroRNAs Profile of PCOS and Identification of Novel Non-Invasive Biomarkers
- W. Long, Chun Zhao, +5 authors J. Liu
- Biology, Medicine
- Cellular Physiology and Biochemistry
- 28 April 2014
Background: Polycystic ovary syndrome (PCOS), the most common endocrinopathy in women of reproductive age, is characterized by polycystic ovaries, chronic anovulation, hyperandrogenism and insulin… Expand
miR-148a is Associated with Obesity and Modulates Adipocyte Differentiation of Mesenchymal Stem Cells through Wnt Signaling
Obesity results from numerous, interacting genetic, behavioral, and physiological factors. Adipogenesis is partially regulated by several adipocyte-selective microRNAs (miRNAs) and transcription… Expand
Postoperative Cognitive Dysfunction: Current Developments in Mechanism and Prevention
- W. Wang, Yan Wang, +8 authors F. Wang
- Medical science monitor : international medical…
- 12 October 2014
Postoperative cognitive dysfunction (POCD) is a subtle disorder of thought processes, which may influence isolated domains of cognition and has a significant impact on patient health. The reported… Expand
Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress.
- Xiaowei Lu, C. Ji, +8 authors X. Guo
- Chemistry, Medicine
- International journal of pharmaceutics
- 22 June 2009
Resveratrol has been reported to protect several types of cells against beta-amyloid peptide (Abeta) toxicity by scavenging reactive oxygen species (ROS) and inactivating caspase-3. However, other… Expand
Feeder-Free Derivation of Human Induced Pluripotent Stem Cells with Messenger RNA
The therapeutic promise of induced pluripotent stem cells (iPSCs) has spurred efforts to circumvent genome alteration when reprogramming somatic cells to pluripotency. Approaches based on episomal… Expand
Change in circulating microRNA profile of obese children indicates future risk of adult diabetes.
PURPOSE Childhood obesity increases susceptibility to type 2 diabetes (T2D) in adults. Circulating microRNAs (miRNAs) in serum have been proposed as potential diagnostic biomarkers, and they may… Expand
Identification of maternal serum microRNAs as novel non-invasive biomarkers for prenatal detection of fetal congenital heart defects.
- Shasha Zhu, L. Cao, +9 authors Zhangbin Yu
- Biology, Medicine
- Clinica chimica acta; international journal of…
- 23 September 2013
BACKGROUND Congenital heart defects (CHD) are the most common form of malformation during embryonic development. Circulating miRNAs have recently been shown to serve as diagnostic/prognostic… Expand
Identification and characterization of NYGGF4, a novel gene containing a phosphotyrosine-binding (PTB) domain that stimulates 3T3-L1 preadipocytes proliferation.
A novel gene named NYGGF4, which was expressed at a higher level in obese subjects, was isolated and characterized. It is a 1527-bp cDNA, containing 753 nucleotides of an ORF (open reading frame)… Expand
Association between manganese superoxide dismutase (MnSOD) Val-9Ala polymorphism and cancer risk - A meta-analysis.
A growing body of evidence suggests that reactive oxygen species (ROS) play an important role in human cancers. Manganese superoxide dismutase (MnSOD) is the major antioxidant in the mitochondria,… Expand