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AlphaInterferon Inhibits Human T-Cell Leukemia Virus Type 1 Assembly byPreventing Gag Interaction withRafts
ABSTRACT Alpha-2a interferon (IFN-α2a) has beneficial clinical effects on human T-cell leukemia virus type 1 (HTLV-1) infection, but its antiviral mechanism of action is unknown. Antiviral effects ofExpand
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Human T-cell leukemia virus type 1 blunts signaling by interferon alpha.
Although many animal viruses block the interferon (IFN) signaling pathway, this issue has not been previously investigated in retrovirus-infected cells. For this purpose, an infectious molecularExpand
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Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1
Multiple sclerosis is an immune-mediated brain disease ameliorated by interferon-beta therapy. Immune responses to IFN-alpha and IFN-beta are sometimes subnormal in MS peripheral blood mononuclearExpand
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Membrane lymphotoxin is required for resistance to Theiler's virus infection.
Lymphotoxin (LT) and tumor necrosis factor (TNF) are important in immune system development and function. LT consists of soluble LT-alpha(3), which binds to TNF-R1 and TNF-R2, and membraneExpand
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Effect and mechanism of long noncoding RNAs HOTAIR on occurrence and development of gastric cancer
In this study, we aimed at looking for the long noncoding RNA (lncRNA) abnormally expressed in gastric cancer (GC) tissues and analyzing the association of its expression level with theExpand
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Vitamin D Enhances Interferon-beta Response in Multiple Sclerosis (P3.103)
Objective: Determine molecular effect of Vitamin D3 on interferon-beta response in mononuclear cells (MNC) Background: Oral vitamin D supplements have additive effects on IFN-b therapy in reducingExpand
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Immunological kidney diseases (PP-098)