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Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells
The survivin protein, a member of the inhibitors of apoptosis (IAP) family, has gained popularity as a therapeutic target for cancer due to its selective expression in tumor cells and its significantExpand
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Clinicopathological significance of oestrogen receptor expression in non-small cell lung cancer
Objective To investigate the expression and clinicopathological significance of the oestrogen receptor (ER) in non-small cell lung cancer (NSCLC). Methods ER expression was examined byExpand
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Survivin expression in human lung cancer and the influence of its downregulation on the biological behavior of human lung cancer cells.
The aim of the present study was to detect the expression of survivin in human lung cancer and to investigate the influence of its downregulation on the biological behavior of A549 lung cancer cells.Expand
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Therapeutic effects of sorafenib on the A549/DDP human lung adenocarcinoma cell line in vitro.
The aim of the present study was to observe the effects of sorafenib on the proliferation, apoptosis and invasion of A549/DDP cisplatin-resistant lung adenocarcinoma cells cultured in vitro. TheExpand
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Stem cells with FGF4-bFGF fused gene enhances the expression of bFGF and improves myocardial repair in rats.
The aim of this study was to investigate whether the modification of bone marrow-derived mesenchymal stem cells (BMSCs) with the fused FGF4 (fibroblast growth factor 4)-bFGF (basic fibroblast growthExpand
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Effect and mechanism of miR-146a on malignant biological behaviors of lung adenocarcinoma cell line
The aim of the present study was to assess the expression of microRNA-146a (miR-146a) in human lung adenocarcinoma cells, its effect on cellular behaviors, and the underlying molecular mechanisms.Expand
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Interleukin-18 suppresses angiogenesis and lymphangiogenesis in implanted Lewis lung cancer
ObjectiveTo investigate the effects of interleukin-18 (IL-18) on implanted Lewis lung cancer in suppressing angiogenesis and lymphangiogenesis.MethodsOne week after hypodermic inoculation of LewisExpand
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Coronary effluent from postconditioned hearts promotes survival of mesenchymal stem cells under hypoxia
Abstract Objectives. Mesenchymal stem cells are sensitive to hypoxia under myocardial micro-environment of ischemia and reperfusion. Ischemic postconditioning, which is cardioprotective againstExpand
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Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.
The present study aimed to analyze the expression levels of adenosine diphosphate ribosylation factor guanylate kinase 1 (ASAP1) and focal adhesion kinase (FAK) in gastric cancer (GC) tissues inExpand
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