X. Chen

Publications69
h-index9
Citations225
Highly Influential Citations4
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[Relationship between LAPTM4B gene polymorphism and susceptibility of lung cancer].
BACKGROUND It has been proved that lysosome-associated protein transmembrane 4 beta (LAPTM4B) plays an important role in tumorigenesis, the *2/*2 genotype of LAPTM4B was closely related to liver… Expand
  • 28
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[Relationship between genetic polymorphism of GSTT1 gene and inherent susceptibility to lung cancer in Han population in Sichuan, China].
BACKGROUND Some studies have supposed that glutathione S-transferases (GSTs) may be involved in detoxification of carcinogens, especially from tobacco smoke. Therefore, polymorphism of GSTs has been… Expand
  • 12
  • 1
[A case-control study on the association between genetic polymorphisms of metabolizing enzymes CYP2D6 and susceptibility to lung cancer].
  • Z. Guo, Q. Zhou, +7 authors J. Yang
  • Biology, Medicine
  • Zhongguo fei ai za zhi = Chinese journal of lung…
  • 20 April 2005
BACKGROUND Genetic polymorphism in metabolic enzymes, which are involved in metabolism of environmental carcinogens, have been thought to be related to susceptibility of lung cancer. The aim of this… Expand
  • 4
  • 1
Metformin Protects Neurons against Oxygen-Glucose Deprivation/Reoxygenation -Induced Injury by Down-Regulating MAD2B
Background/Aims: Metformin, the common medication for type II diabetes, has protective effects on cerebral ischemia. However, the molecular mechanisms are far from clear. Mitotic arrest deficient… Expand
  • 17
[Establishment and their biological characteristics of clonal cell subpopulations (NL9980 and L9981) from a human lung large cell carcinoma cell line (WCQH-9801)].
  • Q. Zhou, Y. Wang, +4 authors Z. Sun
  • Biology, Medicine
  • Zhongguo fei ai za zhi = Chinese journal of lung…
  • 20 December 2003
BACKGROUND To explore the possibility of separating and establishing clonal cell subpopulations with different metastatic phenotype from a human lung large cell carcinoma cell line (WCQH-9801), to… Expand
  • 26
miR-1271-5p inhibits cell proliferation and induces apoptosis in acute myeloid leukemia by targeting ZIC2
MicroRNAs (miRNAs) have been demonstrated to regulate the progression of numerous types of cancer, including acute myeloid leukemia (AML). Previous studies demonstrated that miR-1271-5p functions as… Expand
  • 7
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[A study on apoptosis of nasopharyngeal carcinoma cell line induced by Tanshinone II A and its molecular mechanism].
OBJECTIVE To assess effect of Tanshinone II A on the apoptosis of human nasopharyngeal carcinoma (NPC) cell line CNE-1 and inquire into the mechanism there in involved. METHODS The CNE-1 cells… Expand
  • 11
[Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer].
  • D. Li, Q. Zhou, +6 authors G. Che
  • Biology, Medicine
  • Zhongguo fei ai za zhi = Chinese journal of lung…
  • 20 February 2005
BACKGROUND Lung cancer is the leading cause of malignant tumor death among Chinese population. It has been known that the development of lung cancer may be associated with genetic po-lymorphism of… Expand
  • 15
[Clinical study on efficacy and safety of labor analgesia with inhalation of nitrous oxide in oxygen].
OBJECTIVE To investigate the efficacy and safety of labor analgesia with inhalation of 50% nitrous oxide in oxygen. METHODS A total of 1300 cases of term primiparous women in labor were divided… Expand
  • 16
[Regulation of sonic hedgehog on vascular endothelial growth factor, basic fibroblast growth factor expression and secretion in bone marrow mesenchymal stem cells].
OBJECTIVE Sonic hedgehog (Shh) signaling pathway is involved in an important part of regulating angiogenesis. To investigate the effects of recombinant Shh N-terminate (rShh-N) on the expression and… Expand
  • 11