• Publications
  • Influence
Effect of St. John’s wort supplementation on the pharmacokinetics of bupropion in healthy male Chinese volunteers
  • H-P Lei, X-Y Yu, +5 authors H. Zhou
  • Medicine
  • Xenobiotica; the fate of foreign compounds in…
  • 11 March 2010
The objective of this study was to investigate the effects of continuous St. John’s wort administration on single-dose pharmacokinetics of bupropion, a substrate of cytochrome P450 (CYP) 2B6, inExpand
  • 20
  • 2
Role of ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza
  • X-Y Yu, Z-W Zhou, +7 authors S. Zhou
  • Chemistry, Medicine
  • Xenobiotica; the fate of foreign compounds in…
  • 1 April 2007
There is an increasing use of herbal medicines worldwide, and the extracts from the root of Salvia miltiorrhiza are widely used in the treatment of angina and stroke. In this study, we investigatedExpand
  • 13
  • 1
A novel rat model of chronic heart failure following myocardial infarction.
  • Y-H Fu, Q-X Lin, +9 authors X-Y Yu
  • Medicine
  • Methods and findings in experimental and clinical…
  • 1 July 2009
In this report, we describe an improved method for the establishment of reproducible congestive heart failure (CHF) in a rat model. The area of myocardial infarction (MI) after ligation of the leftExpand
  • 10
  • 1
Effects of visfatin on proliferation and collagen synthesis in rat cardiac fibroblasts.
The proliferation of cardiac fibroblasts (CFs) and excessive extracellular matrix protein accumulation are the basic pathological processes of myocardial fibrosis. Visfatin is a novel adipokineExpand
  • 21
TATDN1 promotes the development and progression of breast cancer by targeting microRNA-140-3p.
OBJECTIVE To explore whether long non-coding RNA (lncRNA) TATDN1 can promote the proliferation and cell cycle progression of breast cancer cells by adsorbing microRNA-140-3p, thus participating inExpand
  • 2
HSP20-mediated cardiomyocyte exosomes improve cardiac function in mice with myocardial infarction by activating Akt signaling pathway.
OBJECTIVE To explore the role of heat shock protein 20 (HSP20)-mediated cardiomyocyte exosomes in the cardiac function in mice with myocardial infarction via the activation of the protein kinase BExpand
  • 2
Enhanced angiotensin converting enzyme 2 regulates the insulin/Akt signalling pathway by blockade of macrophage migration inhibitory factor expression
British Journal of Pharmacology (2008) 153, 621; doi:10.1038/sj.bjp.0707614
  • 1