X. Q. Luo

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Deamination of adenosine on pre-mRNA to inosine is a recently discovered process of posttranscription modification of pre-mRNA, termed A-to-I RNA editing, which results in the production of proteins not inherent in the genome. The present study aimed to identify a role for A-to-I RNA editing in the development of microvascular lung injury. To that end, the(More)
We use the quantum action to study quantum chaos at finite temperature. We present a numerical study of a classically chaotic 2-D Hamiltonian system-harmonic oscillators with anharmonic coupling. We construct the quantum action non-perturbatively and find temperature dependent quantum corrections in the action parameters. We compare Poincaré sections of the(More)
Rapidly accumulating information about the structures and functions of transmembrane proteins in the class of G-protein-coupled receptors is facilitating the exploration of molecular details in the processes of cellular signal transduction. We have described recently a 3-D molecular model of the transmembrane portion of the 5-HT2A type of receptor of the(More)
We investigate the bound states of the Yukawa potential V (r) = −λ exp(−αr)/r, using different algorithms: solving the Schrödinger equation numerically and our Monte Carlo Hamiltonian approach. There is a critical α = α C , above which no bound state exists. We study the relation between α C and λ for various angular momentum quantum number l, and find in(More)
The chiral phase transition induced by a charged scalar field is investigated numerically in a lattice fermion-gauge-scalar model with U(1) gauge symmetry, proposed recently as a model for dynamical fermion mass generation. For very strong gauge coupling the transition is of second order and its scaling properties are very similar to those of the(More)
The Monte Carlo (MC) Hamiltonian is a new stochastic method to solve many-body problems. The MC Hamiltonian represents an effective Hamiltonian in a finite energy window. We construct it from the classical action via Monte Carlo with importance sampling. The MC Hamiltonian yields the energy spectrum and corresponding wave functions in a low energy window.(More)
We construct an effective low-energy Hamiltonian from the classical action via Monte Carlo with importance sampling. We use Monte Carlo (i) to compute matrix elements of the transition amplitude and (ii) to construct stochastically a basis. The MC Hamil-tonian allows to obtain energies and wave functions of low-lying states. It allows also to compute(More)
In order to extend the recently proposed Monte Carlo Hamiltonian to many-body systems, we suggest to concept of a stochastic basis. We apply it to the chain of N s = 9 coupled anharmonic oscillators. We compute the spectrum of excited states in a finite energy window and thermodynamical observables free energy, average energy, entropy and specific heat in a(More)