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Algorithms derived from measurements of short-peptide (8-10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as K(b), can bind well over 1 million different peptides with significant affinity (<500 nM), a level of ligand-binding promiscuity approaching the level of heat shock protein binding of unfolded(More)
Urine release (micturition) serves an essential physiological function as well as a critical role in social communication in many animals. Here, we show a combined effect of olfaction and social hierarchy on micturition patterns in adult male mice, confirming the existence of a micturition control center that integrates pro- and anti-micturition cues.(More)
In this paper, by employing a fixed-point theorem in cones, we study a kind of higher-dimension impulsive functional differential equation with parameter as follows: x' = A(t)x(t) + lambdaf(t, x<sub>t</sub>), t npar tau<sub>k</sub>, Deltax|<sub>t</sub> <sub>=</sub> <sub>tau</sub> <sub>k</sub> = I<sub>k</sub>(x(tau<sub>k</sub>)), t = tau<sub>k</sub>, k isin(More)
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