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Statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, are widely used cholesterol-lowering drugs. Convincing evidence indicates that statins stimulate apoptotic cell death in several types of proliferating tumor cells in a cholesterol-lowering-independent manner. The objective here was to elucidate the molecular mechanism by(More)
Epithelial ovarian cancer (EOC) has the highest mortality rate among gynecological malignancies owing to poor screening methods, non-specific symptoms and limited knowledge of the cellular targets that contribute to the disease. Cyclin G2 is an unconventional cyclin that acts to oppose cell cycle progression. Dysregulation of the cyclin G2 gene (CCNG2) in a(More)
Following the online publication of this article, the authors noticed an error in the presentation of one of the authors' names. 'B Yang' has now been corrected to 'BB Yang'. The authors apologise for any inconvenience caused by this error. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The(More)
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