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BACKGROUND Roughly half the world's population live in dengue-endemic countries, but no vaccine is licensed. We investigated the efficacy of a recombinant, live, attenuated tetravalent dengue vaccine. METHODS In this observer-masked, randomised, controlled, monocentre, phase 2b, proof-of-concept trial, healthy Thai schoolchildren aged 4-11 years were(More)
BACKGROUND Dengue infection is one of the most important mosquito-borne diseases. More data regarding the disease burden and the prevalence of each clinical spectrum among symptomatic infections and the clinical manifestations are needed. This study aims to describe the incidence and clinical manifestations of symptomatic dengue infection in Thai children(More)
BACKGROUND There is an urgent need to field test dengue vaccines to determine their role in the control of the disease. Our aims were to study dengue epidemiology and prepare the site for a dengue vaccine efficacy trial. METHODS AND FINDINGS We performed a prospective cohort study of children in primary schools in central Thailand from 2006 through 2009.(More)
To the Editor: Infection with infl uenza A pandemic (H1N1) 2009 has been reported worldwide following initial identifi cation of the virus in April 2009 (1). The groups at highest risk for infection or infl uenza-related complications include pregnant women and children (2). We report a case of pandemic (H1N1) 2009 infection in a newborn whose mother became(More)
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