Wuqing Ouyang

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Kinetin (Kn) is a cytokinin growth factor that exerts several anti-aging and antioxidant effects on cells and organs. To investigate the mechanism underlying apoptotic events in aging cells induced by D-galactose (D-gal), we examined the effect of Kn delivered via nuchal subcutaneous injection on D-gal-induced aging and apoptosis in rats. Our results showed(More)
Received: Revised: Accepted: The molecular mechanisms specifying anti-oxidative and anti-aging action of kinetin (Kn) on the splenic oxidative damage of aging rats are poorly understood. Here, the Sprague Dawley (SD) rats (Rattus norregicus) aging model was proposed by napes subcutaneous injection of D-galactose, and anti-aging group were subsequently dealt(More)
OBJECTIVE To compare effects of vinblastine (VLB) nanoparticles (NPS) and VLB physiologic saline solution on inhibiting glioma cell lines C6 growth and inducting its apoptosis. METHOD Glioma cell lines C6 were respectively treated with 500 micro x L(-1) VLB NPS and VLB physiologic saline solution for 7 days. Amount of cells were counted by blood cell(More)
OBJECTIVE To prepare an O/W ginseng saponins-based nanoemulsion and investigate its amplified immune response. METHOD The formulation of ginseng saponins-based nanoemulsion was optimized via the range of nanoemulsion zone in phase diagrams and the solubility of ginseng saponins. Its physicochemical properties were investigated, including morphology,(More)
Increasing evidence indicates that aluminum exposure and oxidative stress play crucial roles in the initiation and development of Alzheimer's disease (AD). Aluminum chloride (AlCl3) and d-galactose (d-gal) combined treatment of mice is considered as an easy and cheap way to obtain an animal model of AD. Kinetin is a plant cytokinin, which is also reported(More)
Oxidative stress is considered as one of key factors related to Alzheimer’s disease (AD), while kinetin (KT) has been reported to exert anti-oxidative activities as well as neuroprotective effects both in vivo and in vitro. Thus, in this study, the neuroprotective effects of KT against glutamate-induced oxidative toxicity in HT22 cells were investigated. To(More)
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