Wulf-ingo Jung

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PURPOSE To prospectively use compact avalanche photodiodes instead of photomultiplier tubes to integrate a positron emission tomographic (PET) detector and a 7-T magnetic resonance (MR) imager. MATERIALS AND METHODS All animal experiments were performed in accordance with the University of Tübingen guidelines and the German law for the protection of(More)
Based on the phase difference method as described by Nayler et al. we developed a gradient-echo sequence, which refocuses flow related phase shifts even for infants with their higher peak velocity, higher acceleration and faster heart rates. A repetition time (TR) of 15 ms provides a high temporal resolution for dynamic studies. Modification of the(More)
Friedreich's ataxia is a neurodegenerative disease frequently associated with hypertrophic cardiomyopathy. We have determined mitochondrial ATP, phosphocreatine, and intracellular inorganic phosphate levels by 31P nuclear magnetic resonance spectroscopy in the heart of 11 Friedreich's ataxia patients and 11 healthy controls. For the first time, to our(More)
In chemical shift resolved spectroscopic imaging (CSI) temporal changes in the static magnetic field (drift) can lead to distortions of the phase encoding process. This can result in localization artifacts. The extent of the artifact depends on the size of the drift, the number of acquisitions, as well as on the combination of the size of the field of view(More)
Magnetic resonance (MR) has become a new tool for noninvasive characterization of bone marrow in patients with hematological disorders in the past few years. Experiences gained from1H MR imaging and spectroscopic investigations in 48 healthy volunteers and more than 130 patients with hematological disorders are reported and interpreted. Twenty-four of the(More)
Localized 3~p-NMR spectroscopy can be used to gain insight into the metabolism of the human myocardium. Typically, the signals of phosphocreatine (PCr), adenosinetriphosphate (ATP), 2,3-diphosphoglycerate (2,3-DPG), and phosphodiesters (PDE) are observed. Depending on the resolution of the spectra, the signal from inorganic phosphate (Pi) can also be(More)
Recently, Clarke et al., (Clarke K, Kashiwaya Y, King MT, Gates D, Keon CA, Cross HR, Radda GK, Veech RL. The β/α peak height ratio of ATP. A measure of free [Mg free 2+ ] using31 P NMR, J. Biol. Chem. 1996;271:21142–21150.) reported a new method to noninvasively determine the concentration of intracellular free magnesium ([Mg free 2+ ]) based on the(More)
corum, who peacefully coexist in polygynous nests. Nevertheless, their fighting techniques are strongly reminiscent of the behaviors in several closely related species, the socially parasitic Leptothoracini. In some of these ants, young females invade colonies of a related species and kill the resident queen (e.g., [11]). In a way similar to that of L.(More)
Localized proton decoupled31Pin vivo NMR spectroscopy of the human calf muscle was performed using a 1.5-T whole-body imager and the slice selective two-dimensional chemical-shift-imaging (2D-CSI) technique. The31P-31P coupling constants and the chemical shifts of ATP were compared in gastrocnemius and soleus. Significant differences were found in the(More)
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