Wui Kheun Ong

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BACKGROUND AND PURPOSE Increases in intracellular cyclic AMP (cAMP) augment the release/secretion of glucagon-like peptide-1 (GLP-1). As cAMP is hydrolysed by cAMP phosphodiesterases (PDEs), we determined the role of PDEs and particularly PDE4 in regulating GLP-1 release. EXPERIMENTAL APPROACH GLP-1 release, PDE expression and activity were investigated(More)
Current classification techniques use word matching and clustering techniques to classify webpages. These techniques use ad hoc approach of checking and matching the entire keywords in a webpage for classification. These methods are efficient but not without problems. In general, they suffer from the following problems 1) As they use brute force matching(More)
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