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BACKGROUND There are still concerns about the oncologic safety of stent insertion for colorectal cancer obstruction. This study investigated whether the use of stents as a bridge to surgery negatively affect the long-term outcome compared to curative surgery for left-sided colorectal cancer obstruction. METHODS Between January 2004 and December 2009,… (More)
A very simple and cheap linker has been used for solid-phase synthesis of peptide aldehydes. Protected amino acid aldehydes are immobilized on 2-Cl(trt) resin as oxazolidine formation via diethanolamine. After classical Fmoc SPPS, treatment of the resin with AcOH/DCM/H(2)O (8:1:1) affords peptide aldehydes in high yield and purity.
UNLABELLED METHODOLOGY/AIMS: This study was conducted to compare the oncologic outcomes of transanal excision and radical resection in pathologic stage I rectal cancer. Ninety-six consecutive patients with stage I rectal cancer treated surgically between January 2000 and December 2009 were enrolled. Thirty-one patients underwent full-thickness transanal… (More)