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Paclitaxel is recommended as a first-line chemotherapeutic agent against ovarian cancer, but drug resistance becomes a major limitation of its success clinically. The key molecule or mechanism associated with paclitaxel resistance in ovarian cancer still remains unclear. Sex-determining region Y-box 2 (SOX2) is of vital importance in the regulation of stem(More)
BACKGROUND Aberrant expression of long non-coding RNAs (lncRNAs) is associated with prognosis of gastric cancer, some of which could be further evaluated as potential biomarkers. In this study, we attempted to identify a specific lncRNA signature to predict the prognosis of gastric cancer. MATERIAL AND METHODS The genome-wide lncRNA expression in the(More)
Protein-coding genes and non-coding RNAs cooperate mutually in cells. Integrative analysis of protein-coding and non-coding RNAs may facilitate characterizing tumor heterogeneity. We introduced integrated consensus clustering (ICC) method to integrate mRNA, miRNA and lncRNA expression profiles of 431 primary clear cell renal cell carcinomas (ccRCCs). We(More)
BACKGROUND In schizophrenia, executive dysfunction is the most critical cognitive impairment, and is associated with abnormal neural activities, especially in the frontal lobes. Complexity estimation using electroencephalogram (EEG) recording based on nonlinear dynamics and task performance tests have been widely used to estimate executive dysfunction in(More)
Multiple reflection signals between the probe and the antenna is always ignored in frequency domain near field measurement, which can be reduced by technique such as time gate in the time domain near field measurement sometimes. There are few articles to study about influence of the multiple reflection error affecting the result of the test for it is(More)
Time domain near field measurement theory was first present in the 1994, since then practical test verified the feasibility of the measurement technology. However, error system of time domain near field measurement has not been summarized as system in frequency domain measurement which makes time domain measurement can not be applied in engineering tests as(More)
Both tumor and adjacent normal tissues are valuable in cancer research. Transcriptional response profiles represent the changes of gene expression levels between paired tumor and adjacent normal tissues. In this study, we performed a pan-cancer analysis based on the transcriptional response profiles from 633 samples across 13 cancer types. We obtained two(More)
At present, a complete measurement system has been built up successfully by our laboratory, besides its engineering implement has been accomplished also. We can show an antenna’s radiation field in a form of 3D animation dynamically with this measurement system, which demonstrates the time-domain near-field measurement theory and the time-domain near-field(More)
Gastric cancer is an aggressive cancer that is often diagnosed late. Early detection and treatment require a better understanding of the molecular pathology of the disease. The present study combined data on gene expression and regulatory levels (microRNA, methylation, copy number) with the aim of identifying key genes and pathways for gastric cancer. Data(More)
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