Wouter van den Bos

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In this functional magnetic resonance imaging study, we examined developmental changes in the brain regions involved in reactions to unfair allocations. Previous studies on adults suggested that reactions to unfairness are not only affected by the distribution itself but also by the ascribed intentionality of the proposer. In the current study, we employed(More)
Irreversible electroporation (IRE) is a novel minimally invasive therapy for prostate cancer using short electric pulses to ablate prostate tissue. The purpose of this study is to determine the IRE effects in prostate tissue and correlate electrode configuration with the histology of radical prostatectomy (RP) specimens. We hypothesize that the area within(More)
Focal therapy can offer the middle ground for treatment between active surveillance and radical therapy in patients with low- and intermediate-risk prostate cancer. Factors that prohibit focal therapy from being standard of care are numerous. Several consensus projects have been conducted to position the utilization of imaging and trial design in focal(More)
Knowing how to adapt your behavior based on feedback lies at the core of successful learning. We investigated the relation between brain function, grey matter volume, educational level and IQ in a Dutch adolescent sample. In total 45 healthy volunteers between ages 13 and 16 were recruited from schools for pre-vocational and pre-university education. For(More)
With both its high prevalence and myriad of negative outcomes, Attention-Deficit/Hyperactivity Disorder (ADHD) demands a careful consideration of the efficacy of its treatment options. Although the benefits of medication have a robust empirical background, nonpharmaceutical interventions evoke particular interest, as they are often viewed more favorably by(More)
In this issue of Developmental cognitive neuroscience Shulman nd colleagues (n.d.) and Nelson and colleagues (n.d.) present wo heuristic models of cognitive development. Shulman and coleagues review the current evidence in favor of dual systems (DS) odels, which suggests that enhanced risk taking in adolescents s the consequence of an imbalance between an(More)
Adversity impacts many aspects of psychological and physical development including reward-based learning and decision-making. Mechanisms relating adversity and reward processing in children, however, remain unclear. Here, we show that adversity is associated with potentiated learning from positive outcomes and impulsive decision-making, but unrelated to(More)
Older adults (OA) need to make many important and difficult decisions. Often, there are too many options available to explore exhaustively, creating the ubiquitous tradeoff between exploration and exploitation. How do OA make these complex tradeoffs? We investigated age-related shifts in solving exploration-exploitation tradeoffs depending on the complexity(More)
Scaffolds that serve as synthetic mimics of the extracellular matrix have applications in wound healing, tissue engineering, and stem cell expansion. When cells are cultured in these tunable matrices, little is known about local microenvironmental changes during degradation and remodeling. Methods that provide quantitative and predictable information about(More)
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