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  • J. Carolina Visser, Willem M C Dohmen, Wouter L J Hinrichs, Jörg Breitkreutz, Henderik W Frijlink, Herman J. Woerdenbag
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • 1 May 2015
  • The quality by design (QbD) approach was applied for optimizing the formulation of extemporaneously prepared orodispersible films (ODFs) using Design-Expert® Software. The starting formulation wasContinue Reading
  • Parinda Srinarong, Johan H. Faber, Marinella R Visser, Wouter L J Hinrichs, Henderik W Frijlink
  • Chemistry, Medicine
  • European journal of pharmaceutics and…
  • 1 September 2009
  • In this study, it was shown that the incorporation of superdisintegrants in solid dispersion tablets containing a high drug load can strongly enhance the dissolution rate of the highly lipophilicContinue Reading
  • Wouter L J Hinrichs, Fj Alvarez Manceñido, +4 authors Henderik W Frijlink
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • 1 March 2006
  • In a previous study we have shown that the oligosaccharide inulin can prevent aggregation of poly(ethylene glycol) (PEG) coated plasmid DNA/cationic liposome complexes ("PEGylated lipoplexes") duringContinue Reading
  • Naomi Teekamp, Luisa Fernanda Giraldo Duque, Henderik W Frijlink, Wouter L J Hinrichs, Peter Olinga
  • Materials Science, Medicine
  • Expert opinion on drug delivery
  • 3 August 2015
  • INTRODUCTION Therapeutic proteins and peptides often require parenteral administration, which compels frequent administration and patient discomfort. This ultimately decreases compliance and leads toContinue Reading