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Due to limits on the availability of the energy source in many mobile user platforms (ranging from handheld devices to portable electronics to deeply embedded devices) and concerns about how much heat can effectively be removed from chips, minimizing the power consumption has become a primary driver for system-on-chip designers. Because of their superb(More)
Gene-set enrichment analyses (GEA or GSEA) are commonly used for biological characterization of an experimental gene-set. This is done by finding known functional categories, such as pathways or Gene Ontology terms, that are over-represented in the experimental set; the assessment is based on an overlap statistic. Rich biological information in terms of(More)
Principal component analysis (PCA) has gained popularity as a method for the analysis of high-dimensional genomic data. However, it is often difficult to interpret the results because the principal components are linear combinations of all variables, and the coefficients (loadings) are typically nonzero. These nonzero values also reflect poor estimation of(More)
Emerging mobile systems integrate a lot of functionality into a small form factor with a small energy source in the form of rechargeable battery. This situation necessitates accurate estimation of the remaining energy in the battery such that user applications can be judicious on how they consume this scarce and precious resource. This paper thus focuses on(More)
The emerging trend toward utilizing chip multi-core processors (CMPs) that support dynamic voltage and frequency scaling (DVFS) is driven by user requirements for high performance and low power. To overcome limitations of the conventional chip-wide DVFS and achieve the maximum possible energy saving, per-core DVFS is being enabled in the recent CMP(More)
Validation studies have been used to increase the reliability of the statistical conclusions for scientific discoveries; such studies improve the reproducibility of the findings and reduce the possibility of false positives. Here, one of the important roles of statistics is to quantify reproducibility rigorously. Two concepts were recently defined for this(More)
Non-targeted metabolomic profiling is used to simultaneously assess a large part of the metabolome in a biological sample. Here, we describe both the analytical and computational methods used to analyze a large UPLC–Q-TOF MS-based metabolomic profiling effort using plasma and serum samples from participants in three Swedish population-based studies of(More)
A common goal of epidemiologic research is to study how two exposures interact in causing a binary outcome. Causal interaction is defined as the presence of subjects for which the causal effect of one exposure depends on the level of the other exposure. For binary exposures, it has previously been shown that the presence of causal interaction is testable(More)
Modern smartphones consume significant power and can hardly provide a full day's use between charging operations even with a 2000 mAh battery. This is in spite of many power management techniques being employed in the smartphones. This paper starts from the observation that modern smartphones waste a significant amount of the battery's stored energy during(More)