Woo-Sung Chang

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PURPOSE Childhood allergies are a serious problem, as they may lead to lifetime chronic disease. Determination of total and specific IgE levels is known to be a diagnostic tool for allergic sensitization; however, IgE levels are affected by various factors, such as age, sex, ethnicity, and geographic area. Thus, we evaluated the distribution of total and(More)
PURPOSE The prevalence of allergic diseases is known to be associated with both demographic and environmental factors. Herein, we aimed to determine significant factors associated with the prevalence of allergic diseases and with total immunoglobulin E (tIgE) and specific immunoglobulin E (sIgE) levels in Korea. METHODS We analyzed unweighted data(More)
PURPOSE Allergic diseases are triggered by Th2-mediated immune reactions to allergens and orchestrated by various immunological factors, including immune cells and cytokines. Although many reports have suggested that childhood is the critical period in the onset of allergic diseases and aging leads to alter the susceptibility of an individual to allergic(More)
Background Airway is one of the main routes for allergen exposure and entering airborne allergens through the airway can initiate allergic responses, resulting in development of allergic asthma. There are various environmental factors that also influence to the airway-mediated immune responses. Among the factors, respiratory syncytial virus (RSV) enables(More)
BACKGROUND Recent evidence suggests that prenatal maternal distress increases the risk of allergic diseases in offspring. However, the effect of prenatal maternal depression and anxiety on atopic dermatitis (AD) risk remains poorly understood. OBJECTIVE We investigated whether prenatal maternal distress is associated with AD risk in offspring and whether(More)
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