Wong Tin Wui

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The applicability of microwave non-destructive testing (NDT) technique in characterization of matrix property of pharmaceutical films was investigated. Hydroxypropylmethylcellulose and loratadine were selected as model matrix polymer and drug, respectively. Both blank and drug loaded hydroxypropylmethylcellulose films were prepared using the(More)
The applicability of visible spectrophotometry technique as a tool to determine the drug content of polymeric film for use as a transdermal drug delivery system was investigated. Hydroxypropylmethycellulose (HPMC) was selected as the matrix polymer and nifedipine as the model drug. Blank and nifedipine-loaded HPMC films were prepared using the solvent(More)
The experimental study presents a brief and comprehensive perspective on the methods of developing a Level A in vitro–in vivo correlation (IVIVC) for extended oral dosage forms of water-insoluble drug domperidone. The study also evaluates the validity and predictability of in vitro–in vivo correlation using the convolution technique by one-compartmental(More)
BACKGROUND Nano-scale carbon systems are emerging alternatives in drug delivery and bioimaging applications of which they gradually replace the quantum dots characterized by toxic heavy metal content in the latter application. OBJECTIVE The work intended to use carbon nanospheres synthesized from biowaste Sago bark for cancer cell imaging applications. (More)
The aim of this study is to investigate Artificial Neural Network (ANN) for prediction of drug contents. Hydroxypropylmethylcellulose and loratadine specifically were selected as model matrix polymer and drug. All 0, 5, 10, 20 and 40 mg drug loaded in hydroxypropylmethylcellulose films were conditioned at the relative humidity of 25, 50 and 75% each prior(More)
Microbial anti-cancer enzymes have been proven to be effective and economical agents for cancer treatment. Aeromonas veronii has been identified as a microorganism with the potential to produce L-glutaminase, an anticancer agent effective against acute lymphocytic leukaemia. In this study, a selective medium of Aeromonas veronii was used to culture the(More)
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