Wong Phakhodee

Publications85
h-index15
Citations1,036
Highly Influential Citations17
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Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana.
TLDR
Tri- and tetra-oxygenated xanthones with di-C5 units or with a C5 and a modified C5 groups are essential for high activities and substitution in the A and C rings has been shown to modify the bioactivity of the compounds.
Bioactive carbazole alkaloids from Clausena wallichii roots.
TLDR
Four new carbazole alkaloids, clausenawallines C-F (1-4), along with 18 known compounds (5-22) were isolated from the roots of Clausena wallichii, and compound 4 showed the highest cytotoxicity against oral cavity cancer (KB) and small-cell lung cancer (NCI-H187) with IC(50) values.
Antibacterial carbazole alkaloids from Clausena harmandiana twigs.
Ph3P/I2-Mediated Synthesis of 3-Aryl-Substituted and 3,4-Disubstituted Coumarins
TLDR
The reaction of a variety of aryl acetic acids containing steric or reactive group with 2-hydroxybenzaldehydes or 2′-Hydroxyacetophenone proceeded smoothly at room temperature to afford the corresponding products in good to excellent yields using inexpensive and readily available reagents.
Antibacterial dihydrobenzopyran and xanthone derivatives from Garcinia cowa stem barks.
Antibacterial compounds from Zanthoxylum rhetsa
TLDR
A new amide, zanthorhetsamide, along with nine known compounds, was isolated from the roots and stem barks of Zanthoxylum rhetsa and exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780.
Clausenawallines G-K, carbazole alkaloids from Clausena wallichii twigs.
Naturally occurring prenylated coumarins from Micromelum integerrimum twigs
Rearranged benzophenones and prenylated xanthones from Garcinia propinqua twigs.
TLDR
The first phytochemical investigation of Garcinia propinqua has led to the isolation and identification of three new compounds, including two rearranged benzophenones and a xanthone, doitunggarcinone C, together with seven known compounds.
Approach to the Synthesis of 2,3-Disubstituted-3H-quinazolin-4-ones Mediated by Ph3P-I2.
TLDR
Key transformation in this convergent approach involves Ph3P-I2-mediated formation of amidine upon condensation of an amide or the intermediate amide with methyl anthranilate, which affords 2,3-disubstituted-3H-quinazolin-4-ones in good to excellent yields under mild conditions.
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