Won Seok Jang

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The KIDSCREEN-52 quality-of-life (KIDSCREEN-52-HRQOL) is a relevant, worldwide tool used for assessing the health-related quality of life in children and adolescents. The purpose of this study was to define measurement properties of the Korean version of the KIDSCREEN-52 HRQOL. The original questionnaire was translated following international translation(More)
The therapeutic use of ionizing radiation (e.g., X-rays and γ-rays) needs to inflict minimal damage on non-target tissue. Recent studies have shown that substance P (SP) mediates multiple activities in various cell types, including cell proliferation, anti-apoptotic responses, and inflammatory processes. The present study investigated the effects of SP on(More)
BACKGROUND It is possible that blood B vitamins level and cognitive function may be affected by dietary intake of these vitamins, no study however has yet been conducted on relationships between B vitamins intake and cognitive function among elderly population in Korea. This study examined the relationship between B vitamins intake and cognitive function(More)
ADP-ribosyl cyclase (ADPR-cyclase) produces a Ca2+-mobilizing second messenger, cyclic ADP- ribose (cADPR), from β-NAD+. A prototype of mammalian ADPR-cyclases is a lymphocyte antigen CD38. Accumulating evidence indicates that ADPR-cyclases other than CD38 are expressed in various cells and organs. In this study, we discovered a small molecule inhibitor of(More)
The Soil and Water Assessment Tool (SWAT) model has been used worldwide for many hydrologic and Non-Point Source (NPS) Pollution analyses on a watershed scale. However, it has many limitations in simulating the Vegetative Filter Strip (VFS) because it considers only ‘filter strip width’ when the model estimates sediment trapping efficiency and does not(More)
The Long Term Hydrologic Impact Assessment (L-THIA) model was previously improved by incorporating direct runoff lag time and baseflow. However, the improved model, called the L-THIA asymptotic curve number (ACN) model cannot simulate pollutant loads from a watershed or instream water quality. In this study, a module for calculating pollutant loads from(More)
BACKGROUND Large glomeruli are a common finding in the early stages of progressive renal disease. We studied the relationship between glomerular surface area (GSA) and clinicopathologic features of IgA nephropathy (IgAN), including renal outcome, to better understand the role of GSA in IgAN. METHODS We analyzed renal biopsy specimens and clinical(More)
Laparoscopic cholecystectomy (LC) is the treatment of choice for acute cholecystitis. However, the morbidity and mortality rates are high in elderly patients or in those with co-morbidities at the time of surgery. Percutaneous cholecystostomy (PC) is a safe treatment for acute inflammation of the gall bladder. This study aimed to evaluate the safety and(More)
This study was to investigate whether the topoisomerase (Top) I inhibitor topotecan and the Top II inhibitor etoposide could modulate the hypoxia-induced HIF-1α expression in non-small cell lung cancer (NSCLC) cell lines. Hypoxic conditions were maintained in a humidified airtight anaerobic incubator flushed with a mixture of gas consisting of 1% O2, 5% CO2(More)
Groundwater management and protection has been facilitated by computational modeling of aquifer vulnerability and monitoring aquifers using groundwater sampling. The DRASTIC (Depth to water, Recharge, Aquifer media, Soil media, Topography, Impact of vadose zone media, and hydraulic Conductivity) model, an overlay and index GIS model, has been used for(More)