Learn More
BACKGROUND The purpose of the study was to evaluate the safety and effects of single-incision laparoscopic anterior resection (SILAR) for sigmoid colon cancer by comparing it with conventional laparoscopic anterior resection (CLAR). METHODS Twenty-four patients who underwent SILAR between April 2010 and July 2011 were case matched 1:2 with patients who(More)
PURPOSE To investigate the efficacy and safety of the transanal tube (TAT) in preventing anastomotic leak (AL) in rectal cancer surgery. METHODS Clinical data of the patients who underwent curative surgery for mid rectal cancer from February 2010 to February 2014 were reviewed retrospectively. Rectal cancers arising 5 to 10 cm above the anal verge were(More)
Primary adenocarcinoma of the appendix is a rare malignancy that constitutes < 0.5% of all gastrointestinal neoplasms. Moreover, primary signet ring cell carcinoma of the appendix is an exceedingly rare entity. We have encountered 15 cases of primary appendiceal cancer among 3389 patients who underwent appendectomy over the past 18 years. In the present(More)
PURPOSE The authors evaluate the prevalence of malnutrition and its effect on the postoperative morbidity of patients after surgery for colorectal cancer. METHODS Three hundred fifty-two patients were enrolled prospectively. Nutritional risk screening 2002 (NRS 2002) score was calculated through interview with patient on admission. Clinical(More)
Transduction with recombinant, replication-defective adenovirus (AdV) vectors encoding a transgene is an efficient method for gene transfer into murine or human dendritic cells (DC). We previously reported that human dendritic cells transduced with recombinant adenovirus encoding the CEA gene (AdVCEA) can effectively induce antigen-specific cytotoxic T(More)
PURPOSE The Niti CAR 27 (ColonRing) uses compression to create an anastomosis. This study aimed to investigate the safety and the effectiveness of the anastomosis created with the Niti CAR 27 in a laparoscopic anterior resection for sigmoid colon cancer. METHODS In a single-center study, 157 consecutive patients who received an operation between March(More)
3-Deazaadenosine (DZA), a potent inhibitor of S-adenosylhomocysteine hydrolase, was previously proposed to induce intrinsic apoptosis in human leukemic cells. In the present study, we analyzed the mechanism underlying the DZA-induced intrinsic apoptotic pathway. DZA activated typical caspase-dependent apoptosis in HL-60 cells, as demonstrated by an(More)
BACKGROUND AND OBJECTIVES The calcium-binding protein S100A4 promotes tumor progression and metastasis. We investigated the expression of S100A4 in colorectal cancer and its clinicopathologic significance in colorectal cancer. METHODS A total of 526 colorectal cancer patients were examined for S100A4 protein by immunohistochemistry using tissue(More)
– Magneto-optical imaging reveal that below 10 K the penetration of magnetic flux in MgB2 films is dominated by dendritic structures abruptly formed in response to an applied field. The dendrites show a temperature-dependent morphology ranging from quasi-1D at 4 K to large tree-like structures near 10 K. This behaviour is responsible for the anomalous noise(More)