Wolfgang Völkel

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Inhibition of fungal lanosterol-14 alpha-demethylase (CYP51) is the working principle of the antifungal activity of azoles used in agriculture and medicine. Inhibition of human CYP51 may result in endocrine disruption since follicular fluid-meiosis activating steroid (FF-MAS), the direct product of lanosterol demethylation, is involved in the control of(More)
In the last decade an important role for the progression of neuronal cell death in Alzheimer's disease (AD) has been ascribed to oxidative stress. trans-4-Hydroxy-2-nonenal, a product of lipid peroxidation, forms conjugates with a variety of nucleophilic groups such as thiols or amino moieties. Here we report for the first time the quantitation of(More)
While one of the authors of the editorial wrote in 2010 in Environmental Health Perspectives " biomonitoring studies should be used by regulatory agencies to assess human exposure levels " and further on " Center of Disease Control (CDC) analytical procedure … is the gold standard " (Vandenberg et al. 2010b), Vandenberg and Prins praise the studies of Hass(More)
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