Wolfgang Römer

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Oxidative stress is considered to be an important pathophysiological condition to promote cell death in a broad variety of disorders, such as cardiovascular and neurodegenerative diseases. Scavestrogens, structurally derived from estradiol, are potent radical scavengers and inhibitors of iron-induced cell damage in vitro. In this study the potential(More)
Antioxidant effects of delta 8,9-dehydro derivatives of 17 alpha-estradiol and 17 beta-estradiol were investigated using four different in vitro models: rat synaptosomal lipid peroxidation induced by Fenton's reagent, Fe(II)-chelating activities, the formation of superoxide anion radicals, and total antioxidative activities. The parent molecules, 17(More)
Antioxidant effects of N,N-dimethyl-p-toluidine, p-cresol, and p-(hydroxy)thioanisol 17 alpha-substituted analogs of 17 beta-estradiol and their delta 9(11)-dehydro homologs were investigated using four different in vitro models: rat synaptosomal lipid peroxidation induced by Fenton's reagent, Fe(II)-chelating activities, the formation of superoxide anion(More)
Using Horney's clinical concepts and Leary's circle matrix procedures, this study investigated the Type A and B patterns of personality. Significant findings showed the Type A-B continuum to represent two distinct poles, with the Type A direction reflecting the expansive personality pattern (power and aggressiveness) and the Type B direction reflecting the(More)
Three issues associated with the lack of statistical evaluation of Horney's theory were presented. They are the preference for professional and clinical impression over the use of more objective methods for defining and evaluating behaviors; the difficulty involved in validly assessing the dysfunctional nature of the expansive type; and the disregard of(More)
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