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PURPOSE To evaluate the efficacy and safety of a dexamethasone implant (Ozurdex) alone or in combination with bevacizumab. METHODS Sixty-four eyes were prospectively investigated. Group 1 (22 central retinal vein occlusion (CRVO) and 16 branch retinal vein occlusion (BRVO)) was treated with Ozurdex alone, and group 2 (14 CRVO and 12 BRVO) was treated with(More)
PURPOSE To report on epiretinal membrane (ERM) characteristics and photoreceptor layer integrity of lamellar macular holes (LMHs) and macular pseudoholes (MPHs), and to compare with clinical course in operated and untreated eyes. METHODS We consecutively reviewed the charts of patients with LMH and MPH between 2003 and 2013. For clinical analysis, we(More)
PURPOSE To compare immunocytochemical and ultrastructural characteristics of "lamellar hole-associated epiretinal proliferation" in lamellar macular holes with "conventional epiretinal membrane" in macular pseudoholes. DESIGN A consecutive observational case series, laboratory investigation. METHODS We analyzed surgically excised flat-mounted internal(More)
BACKGROUND To ascertain the morphological changes in the edge structure of femtosecond laser-derived capsulotomy specimens using varying patient interfaces and different laser pulse energies. METHODS In this experimental clinical study femtosecond laser-assisted capsulotomies were performed in 30 eyes using the LenSx femtosecond laser (LenSx, Alcon, Fort(More)
PURPOSE To evaluate cell death and ultrastructural effects on capsulotomy specimens derived from femtosecond laser-assisted cataract surgery. METHODS In 26 eyes, an anterior capsulotomy was performed using a femtosecond laser. In 10 eyes (group 1), the laser-pulse energy was set to 15 μJ using a rigid curved interface and in another 10 eyes (group 2) to 5(More)
BACKGROUND The pathogenesis of central serous chorioretinopathy (CSC) is still poorly understood. An animal model of CSC proved that the mineralocorticoid receptor [1] of the choroid also plays a role in CSC. Since there is still no evidence-based therapy for non-self-limiting CSC, this case series evaluates the effect of oral spironolactone in CSC(More)
PURPOSE To study the microanatomic edge structures of anterior lens capsule specimens derived from manual and femtosecond laser-assisted capsulotomies. SETTING Department of Ophthalmology, Goethe-University, Frankfurt, Germany. DESIGN Experimental study. METHODS Of 60 eyes with lens removal and intraocular lens implantation, 30 received a manual(More)
OBJECTIVES The objective of this retrospective study was to document the extent of thrombus in patients with recurrent and first deep vein thrombosis (DVT). PATIENTS AND METHODS A total of 864 patients with DVT of the leg were enrolled in the study. They were divided into two groups: patients with recurrent DVT (n = 233) of the leg, and patients with(More)
INTRODUCTION To diagnose septic and aseptic loosening 18-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) has been described with good results for hip arthroplasties. The purpose of the present study was to examine whether there is a difference of feasibility in detecting loosening of hip versus knee prostheses by use of (18)F-FDG-PET. (More)
The role of season as a predisposing factor for the development of deep vein thrombosis is controversially discussed. We analysed retrospectively seasonal variations in the occurrence of deep vein thrombosis of the leg in 905 patients between 1996 and 2000. Additionally, we evaluated the relationship between the season and the location of the thrombus. Our(More)