Wojciech Wańha

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AIM The microRNAs (miRs) are small non-coding RNAs which regulate expression of multiple genes involved in atherogenesis. MicroRNA are also present in circulation. The aims of this study were: 1) assessment of expression level of miR-1, miR-208a and miR-423-5p in plasma in patients with STEMI, stable CAD and healthy individuals; 2) evaluation of correlation(More)
BACKGROUND This study compared safety and efficacy of first- and second-generation DES in an unrestricted, real-life population of diabetic patients undergoing PCI. MATERIAL AND METHODS The study was a subanalysis of diabetic patients from the all-comer Katowice-Zabrze Registry of patients undergoing PCI with the implantation of either first-(More)
BACKGROUND The OCTOPUS registry prospectively evaluates the procedural and long-term outcomes of saphenous vein graft (SVG) PCI. The current study assessed the morphology of de novo lesions and in-stent restenosis (ISR) in patients undergoing PCI of SVG. METHODSANDRESULTS Optical coherence tomography (OCT) of SVG lesions in consecutive patients presenting(More)
BACKGROUND/AIMS Clinical benefits of percutaneous treatment of renal artery stenosis (RAS) remain controversial. The aim of this study was to evaluate the effects of renal artery stenting on kidney function and blood pressure (BP) control in the log-term follow-up. Additionally angiographic follow up was performed in selected subgroup of patients. METHODS(More)
RESULTS The binary angiographic SER rate was 10% (32/319) in the patients, 8.4% (32/382) in lesions and 4.4% (33/744) in stent edge segments. In the stent edge segments at post-stenting, OCT-derived lipidic plaque (61% vs. 20%, p<0.001) was more often observed in the SER group, and OCT-measured minimum lumen area (4.13 2.61 mm2 vs. 5.58 2.46 mm2, p1⁄40.001)(More)
BACKGROUND The aim of this study was to evaluate gender differences in the long-term clinical outcomes and safety of patients treated with first- and second generation DES. METHODS The Katowice-Zabrze Registry included 1916 consecutive patients treated with either first or second generation DES. We evaluated major adverse cardiac and cerebrovascular(More)
BACKGROUND Occurrence of a stroke is a major concern in patients undergoing coronary artery bypass grafting (CABG). It remains uncertain whether significant asymptomatic carotid artery stenosis (CAS) is associated with stroke incidence in such patients. AIM To investigate the incidence of cerebrovascular events, myocardial infarction (MI), and death in(More)
BACKGROUND Clinical studies have suggested increased risk of thrombotic events after planned cessation of clopidogrel therapy, due to increased platelet reactivity (platelet rebound); however, in many studies platelet function was not assessed before introducing clopidogrel. Patients who are scheduled to stop clopidogrel therapy, do it abruptly, so a(More)