Wojciech Serednicki

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Recent studies demonstrate that activation of proinflammatory cytokines following injury intensifies the process of nociception. The present investigation assessed the influence of pre-injury pentoxifiline (PTFL, a non-specific cytokine inhibitor) on the development of post-injury nociception in animals and patients. It was established that intrathecal or(More)
Proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-alpha), interleukin-1 (IL-1) and interleukin-6 (IL-6), act as mediators of post-injury inflammation and increase pain sensitivity. Pentoxifylline (PTX) has the property of inhibiting TNF-alpha, IL-1, and IL-6 production. Previous studies revealed that the pre-injury or preoperative(More)
Pentoxifylline does not affect nociception if administered postopera-tively. Proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-a), interleukin-1 (IL-1) and interleukin-6 (IL-6), act as mediators of post-injury inflammation and increase pain sensitivity. Pentoxifylline (PTX) has the property of inhibiting TNF-a, IL-1, and IL-6 production.(More)
Drug interactions are a growing problem in the practice of otolaryngology. The use of drugs in patients treated with polypharmacy generates the risk of adverse drug interactions which requires specialized knowledge and active prevention. The most common interactions encountered by ENT physicians are identified on the basis of the analysis of medical order(More)
OBJECTIVES Mechanical thrombectomy (MT) is not reimbursed by the Polish public health system. We present a description of 5 years of experience with MT in acute stroke in Comprehensive Stroke Centers (CSCs) in Poland. METHODS AND RESULTS We retrospectively analyzed the results of a structured questionnaire from 23 out of 25 identified CSCs and 22 data(More)
OBJECTIVE To describe the successful, clinical use of the Angel(®) Catheter, a device used for the prevention of pulmonary embolism (PE) and central venous access in a critically ill, multi-trauma patient. METHODS Authors report the case of a 35-year-old man, in critical condition with multiple trauma injuries sustained from a fall, who was admitted to(More)
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