Wojciech Marciniak

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Purpose: To evaluate the correlation between the occurrence of age-related cataract (ARC) and the concentration of serum selenium. Methods: A study group included 95 cataract patients (36 men, 59 women), aged 56-89 years (72.4 ± 7.25), not suffering from other ocular diseases or systemic diseases with proven impact on the eye function or on blood levels of(More)
The first aim of our study was to examine the association between common variants in VDR [rs2228570 (FokI), rs1544410 (BsmI), rs7975232 (ApaI), rs731236 (TaqI) and rs11568820 (Cdx2)] and lung cancer risk in the Polish population. Genotyping and statistical analysis which included Chi-square test with Yates correction and haplotype frequency analysis were(More)
Material and methods The study was performed in five groups. For four of them (cancers of the lung, larynx, colon, prostate) and matched healthy controls serum was collected before treatment but during diagnosis. Whereas for breast cancer group serum was collected 1 2 years before tumor diagnosis. Cases and controls in each study groups were matched for(More)
PURPOSE Understanding of the etiology and pathogenesis of pancreatic cancer (PaCa) is still insufficient. This study evaluated the associations between concentrations of selenium (Se) and copper (Cu) in the serum of PaCa patients. MATERIALS AND METHODS The study included 100 PaCa patients and 100 control subjects from the same geographical region in(More)
Iron plays an important role in many metabolic processes, is included in the delivery of oxygen to cells and redox processes. Deficiency or excess of iron can lead to multiple organ failures and in extreme cases to death. The latest studies show that the iron can significantly influence the risk of cancer development and progression. Scientists reported(More)
Studies on the reaction of zinc alkyls with O2 are reported which demonstrate that the selective oxygenation of organozinc compound is viable. The reaction of [EtZn(azol)]n (azol = deprotonated 1-aziridineethanol) with an excess of dry O2 in toluene affords the zinc ethylperoxide [EtOOZn(azol)]2[EtZn(azol)]2, while the analogous reaction between Me2Zn and(More)
Background Zinc is a micronutrient which is essential for human health, playing a role as a cofactor of enzymes such as dehydrogenases, peptidases and component of zinc finger domains. In organism zinc is involved in metabolic pathways, immune processes, maintaining ion balance between other elements. Recently, it has been reported that zinc may play role(More)
Magnesium plays a key role in many essential cellular processes. It is recognized that magnesium deficiency may lead to many disorders like cardiovascular disease, diabetes mellitus, hypertension, myocardial infarction or even cancer. Connection between magnesium concentration in body fluids and cancer occurrence still becomes unclear. Magnesium ions are(More)
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