Avicequinone B sensitizes anoikis in human lung cancer cells
- Arisara Prateep, S. Sumkhemthong, C. Chaotham
- Biology, MedicineJournal of Biomedical Sciences
- 9 April 2018
Avicequinone B sensitized anoikis in human lung cancer cells through down-regulation of anti-apoptosis proteins and integrin-mediated survival signaling.
Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors.
- Wiranpat Karnsomwan, Ponsawan Netcharoensirisuk, T. Rungrotmongkol, W. De-Eknamkul, S. Chamni
- Chemistry, BiologyChemical and pharmaceutical bulletin
- 1 March 2017
Molecular docking results of the in silico three-dimensional steroid 5 α-reductase type 1-reduced nicotinamide adenine dinucleotide phosphate (NADPH) binary complex illustrated that the furanonaphthoquinone moiety and the substituent at furan ring might play a key role as pharmacophores for the steroid 5α- reductase inhibitory activity.
In silico structural prediction of human steroid 5α-reductase type II
- Wiranpat Karnsomwan, T. Rungrotmongkol, W. De-Eknamkul, S. Chamni
- Biology, ChemistryMedicinal Chemistry Research
- 9 March 2016
A comparative structure of 5α-reductase type II was illustrated that derived from the homology modeling, employing a membrane-bound protein, isoprenylcysteine carboxyl methyltransferase as a homologous template, and depicted the well-defined comparative three-dimensional structure applicable for steroid reductase drug design.
Erratum to: In silico structural prediction of human steroid 5α-reductase type II
- Wiranpat Karnsomwan, T. Rungrotmongkol, W. De-Eknamkul, S. Chamni
- BiologyMedicinal Chemistry Research
- 1 July 2017
In silico structural prediction of human steroid 5α-reductase type II
- Wiranpat Karnsomwan, T. Rungrotmongkol, W. De-Eknamkul, S. Chamni
- Biology, ChemistryMedicinal Chemistry Research
- 9 March 2016
A comparative structure of 5α-reductase type II was illustrated that derived from the homology modeling, employing a membrane-bound protein, isoprenylcysteine carboxyl methyltransferase as a homologous template, and depicted the well-defined comparative three-dimensional structure applicable for steroid reductase drug design.
Erratum to: In silico structural prediction of human steroid 5α-reductase type II
- Wiranpat Karnsomwan, T. Rungrotmongkol, W. De-Eknamkul, S. Chamni
- BiologyMedicinal Chemistry Research
- 18 March 2017
Avicequinone B sensitizes anoikis in human lung cancer cells
- Arisara Prateep, S. Sumkhemthong, C. Chaotham
- Biology, ChemistryJournal of Biomedical Sciences
- 9 April 2018
The potential of avicequinone B, a natural furanonaphthoquinone found in mangrove tree to sensitize anoikis in human lung cancer cells is demonstrated to have down-regulation of anti-apoptosis proteins and integrin-mediated survival signaling.