Wing Yee Au

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Using a program specialize, we automatically generated high-performance digital simulation algorithms from a simple interpreter-based simulator. By making simple changes in the simulator and the specisdizer, we generated four types of compiled simulations: the PC-set algorithm, an improvement on the PC-set algorithm, and two compiled versions of the BACKSIM(More)
A 34-year-old Chinese man was admitted with unsteady gait and clumpsiness. Examination showed sensory peripheral neuropathy but accompanied by gross past pointing, dysdiadochokinesia and cerebellar gait. A computerized tomogram scan showed bilateral cerebellar degeneration (Figure 1A arrows) and thinning of folia (Figure 1B). There was mild macrocytic(More)
Addition of cortisol (10(-6) to 10(-8) M) and related glucocorticoid congeners to cultures of rat parathyroid glands stimulated dose-related increases in parathyroid hormone secretion; the addition of deoxycorticosterone or cortexolone was without effect. Cortexolone, however, inhibited the stimulatory activity of cortisol when both were added to the(More)
Dear Editor, A 54-year-old Chinese male hepatitis B virus (HBV) carrier presented with jaundice, cyanosis, and confusion. Despite oxygen supplement, pulse oximetry showed persistent desaturation and investigations showed raised methemo-globin (16.8%, normal <1.5%). There was also grossly raised aspartate and alanine aminotransferase (>6,000 IU), bilirubin(More)
BACKGROUND The best overall treatment strategy for patients with acute promyelocytic leukaemia (APL) in relapse with chemotherapy, bone marrow transplantation (BMT) or arsenic trioxide (As(2)O(3)) based therapy remains undefined. PATIENTS AND METHODS We reviewed the clinical course and treatment outcome of 143 APL cases seen in four major hospitals in(More)
Dear Editor, A 21-year-old man presented with a rapidly growing (9 cm), non-tender right flank mass with superficial excoriation and inflammation (Fig. 1a). The lesion was accompanied by rapid onset of disseminated brown papules, involving the torso, back, and limbs (Fig. 1b). Facial and axillary skins were spared, and there was no particular direction of(More)
Dear Editor, A 63-year-old patient presented with abdominal pain. A computerized tomogram scan showed a gallbladder mass (Fig. 1a). A positron emission tomogram revealed additional FDG-avid lesions in the sternum, ribs, bilateral humeri, vertebral column, and pelvic bone (Fig. 1b). Magnetic resonance imaging confirmed vertebral lytic lesions (Fig. 1c). A(More)
Dear Editor, A 58-year-old man presented with bilateral, persistent steroid refractory vitritis in 2005. Repeated vitreous biopsies in 2006 and 2007 were inconclusive. In late 2008, he developed vertigo and a magnetic resonance imaging (MRI) scan showed an intra-axial infratentorial tumor with marked cerebellar ede-ma. Brain biopsy showed diffuse large B(More)
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