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The use of computational approaches in inhaler development.
TLDR
Computational Fluid Dynamics (CFD) and Discrete Element Modelling (DEM) studies relevant to inhaled drug delivery are reviewed. Expand
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Particle Aerosolisation and Break-up in Dry Powder Inhalers 1: Evaluation and Modelling of Venturi Effects for Agglomerated Systems
ABSTRACTPurposeThis study utilized a combination of computational fluid dynamics (CFD) and standardized entrainment tubes to investigate the influence of turbulence on the break-up and aerosolExpand
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Pharmacopeial methodologies for determining aerodynamic mass distributions of ultra-high dose inhaler medicines.
Three different impactor methodologies, the Andersen cascade impactor (ACI), next-generation impactor (NGI) and multistage-liquid impinger (MSLI) were studied to determine their performance whenExpand
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Does carrier size matter? A fundamental study of drug aerosolisation from carrier based dry powder inhalation systems.
There is plenty of evidence supporting the notion that the size of the carrier influences the aerosolisation performance of drug from a drug-carrier blend. Interestingly, that evidence isExpand
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Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of impaction effects for agglomerated systems.
This study utilised a combination of computational fluid dynamics (CFD) and standardised entrainment tubes to investigate the influence of impaction on the break-up and aerosol performance of a modelExpand
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Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of the influence of grid structures for agglomerated systems.
This study aimed to investigate the influence of grid structures on the break-up and aerosol performance of a model inhalation formulation through the use of standardised entrainment tubes inExpand
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One-pot synthesis of Ag-MWCNT@TiO2 core–shell nanocomposites for photocatalytic reduction of CO2 with water under visible light irradiation
Abstract This work presents for the first time the preparation of silver (Ag)-doped MWCNT@TiO 2 (multi-walled carbon nanotubes@titanium dioxide) core–shell nanocomposites with enhancedExpand
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An Evaluation of Perceptual Depth to Enhance Change Detection
Two experiments investigated the effect of perceptual depth as a cue to highlight unexpected or changing stimuli. We used a new display technology known as a Multi-Layered Display (MLD). The resultsExpand
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3 D printing : an emerging tool for novel microfluidics and lab ‐ on ‐ a ‐ chip applications
many fields such as medicine, chemistry, and biotechnologies (Barry and Ivanov 2004; Beebe et al. 2002; Dittrich and Manz 2006; Hong and Quake 2003; Stone et al. 2004; Thorsen et al. 2002; Wang etExpand
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Processor s Precise Pulse Targets Power PWM
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