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Sphinx-4 is an open source HMM-based speech recognition system written in the Java™ programming language. The design of the Sphinx-4 decoder incorporates several new features in response to current demands on HMM-based large vocabulary systems. Some new design aspects include graph construction for multilevel parallel decoding with multiple feature streams(More)
The Meeting Central prototype is a suite of collaboration tools designed to support distributed meetings. The tools' minimalist design provides only those features that have the most impact on distributed meeting effectiveness. The collaboration suite is built on top of a distributed, extensible, and scalable framework.
Patient vital sign monitoring within hospitals requires the use of non-invasive sensors that are hardwired to bedside monitors. This setup is cumbersome, forcing the patient to be confined to his hospital bed thereby not allowing him to move around freely within the hospital premises. This paper addresses the use of wireless sensor networks for monitoring(More)
To participate in musical improvisations, an interacting system must both generate appropriate musical materials and express those materials appropriately in collaboration with other performers. We have used results from the study of conversation and discourse to identify the major components for a theory of improvisation—listening, composing, and(More)
The c-Myc oncoprotein is strongly induced during the G0 to S-phase transition and is an important regulator of cell cycle entry. In contrast to c-Myc, the putative Myc antagonist Mnt is maintained at a constant level during cell cycle entry. Mnt and Myc require interaction with Max for specific DNA binding at E-box sites, but have opposing transcriptional(More)
  • John J. Rogus, G. David Poznik, Marcus G. Pezzolesi, Adam M. Smiles, Jonathon Dunn, William Walker +7 others
  • 2008
OBJECTIVE Epidemiological and family studies have demonstrated that susceptibility genes play an important role in the etiology of diabetic nephropathy, defined as persistent proteinuria or end-stage renal disease (ESRD) in type 1 diabetes. RESEARCH DESIGN AND METHODS To efficiently search for genomic regions harboring diabetic nephropathy genes, we(More)
In this presentation we will show how the ImprovisationBuilder framework was adapted to our compositions for pianists and computers. Software design issues include: capturing, transforming, and realizing MIDI piano data, and an easy-to-use graphical interface for altering parameters during performance. Compositional issues include: the causal responsorial(More)
The development of siRNA-based asthma therapeutics is currently hampered by a paucity of relevant biomarkers and the need to ascertain tissue-specific gene targeting in the context of active disease. Epithelial STAT6 expression is fundamental to asthma pathogenesis in which inflammatory changes are found throughout the respiratory tract. Therefore, to(More)
BACKGROUND Post-cardiotomy cardiogenic shock (PCCS) has an incidence of 2-6 % after routine adult cardiac surgery. 0.5-1.5 % are refractory to inotropic and intra-aortic balloon pump (IABP) support. Advanced mechanical circulatory support (AMCS) can be used to salvage carefully selected number of such patients. High costs and major complication rates have(More)