William Wai Ki So

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BACKGROUND Recent reports suggested that ultrasound guidance during embryo transfer might improve the pregnancy rate. METHODS A prospective randomized controlled trial was performed to compare embryo transfer under ultrasound guidance versus the clinical touch method. A total of 800 embryo transfers was studied; 400 were randomized to ultrasound-guided(More)
High oestradiol concentrations may be detrimental to the success of in-vitro fertilization (IVF) treatment. A total of 1122 women aged <40 years who were undergoing their first IVF cycle were evaluated retrospectively. Serum oestradiol concentrations on the day of human chorionic gonadotrophin (HCG) administration were categorized into three groups: group A(More)
OBJECTIVE To study the factors affecting the incidence of polyploidy in an assisted reproduction program. DESIGN Retrospective analysis. SETTING University-based subfertility clinic. PATIENTS AND METHODS Subfertile patients were treated in 163 treatment cycles of in vitro fertilization (IVF) or pronuclear stage tubal transfer (PROST). The relationship(More)
OBJECTIVES To investigate the variation of endometrial responsiveness between cycles within the same women undergoing assisted reproduction. METHODS The sonographic endometrial thickness in ovarian stimulation cycles was compared with that of subsequent natural cycles. One hundred and thirty-six ovarian stimulation cycles of in-vitro fertilization and(More)
Forty-six hydropic infants with homozygous alpha-thalassaemia born during a period of 10 years have been reviewed. The incidence was 1:1550 total births, and accounted for 81% of all non-immune hydrops. The male to female ratio was 1:1.4. There was increased incidence of anaemia, pregnancy induced hypertension, antepartum haemorrhage, malpresentation,(More)
OBJECTIVE To determine whether intrauterine insemination (IUI) after ovarian stimulation with human menopausal gonadotropin (hMG) gives a better pregnancy rate (PR) than natural intercourse in couples with subfertility because of subnormal semen. DESIGN Prospective randomized controlled trial. SETTING University based subfertility clinic. PATIENTS(More)
OBJECTIVE To report the experience in sperm extraction from testicular biopsies (TESE) performed from March 1996 to July 1998 in men with non-obstructive azoospermia (NOA). METHODS Comparisons of age, volume of both testes, serum FSH and testosterone in men, and histology of testicular samples in the first cycles between cycles with spermatozoa found and(More)
Of clinical pregnancies in our in vitro fertilisation (IVF) programme, 5.4% were ectopic and 0.85% of clinical pregnancies (15% of ectopic pregnancies) were heterotopic. Ectopic pregnancies were more common after IVF/embryotransfer (ET) than frozen embryotransfer (FET). Although there was a suggestion that tubal factors were more common in those with(More)
One hundred fourteen semen samples from Chinese males were analyzed for routine semen parameters including the semen volume, sperm count, percentage motility, and percentage normal morphology. Of these 114 samples, 54 also had movement characteristics of seminal and swim-up sperm evaluated by the computer image analyzer system (Cellsoft; Cryo Resources Co.,(More)
Data in the Caucasian population suggest that maternal serum alpha-fetoprotein (AFP) and unconjugated oestriol concentrations are reduced and human chorionic gonadotrophin (HCG) concentrations are elevated in pregnancies conceived after in-vitro fertilization (IVF), leading to a higher than expected Down's syndrome screen-positive rate. There are no(More)