William .T.K. Johnson

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Legionella pneumophila is on the United States Environmental Protection Agency (USEPA) Candidate Contaminant list (CCL) as an important pathogen. It is commonly encountered in recycled water and is typically associated with amoeba, notably Naegleria fowleri (also on the CCL) and Acanthamoeba sp. No legionellosis outbreak has been linked to recycled water(More)
Zolpidem is among the most frequently prescribed hypnotic drugs for those who suffer from insomnia. Recent media reports drew attention to driving impairment after zolpidem misuse. This review summarizes the available data on the effects of recommended use and misuse of zolpidem on driving ability and traffic safety. Both experimental studies and roadside(More)
OBJECTIVES The objective of the Fatality Assessment and Control Evaluation (FACE) program is to prevent traumatic occupational fatalities in the United States by identifying and investigating work situations at high risk for injury and formulating and disseminating prevention strategies to those who can intervene in the workplace. SETTING The FACE program(More)
Author affilliations and addresses: 1 Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr Pasadena CA 91109; 2 United States Geological Survey, 2255 N. Gemini Dr. Flagstaff AZ 86001; 3 Applied Physics Laboratory, Johns Hopkins University, 11100 Johns Hopkins Road, Laurel MD 20723; 4 NASA Goddard Institute for Space Studies, 2880(More)
Tumor necrosis factor(TNF), a cytokine secreted by inflammatory cells, has been implicated in several inflammatory disease states. (E)-2(R)-[1(S)-(Hydroxycarbamoyl)-4-phenyl-3-butenyl]-2 isobutyl-2 -(methanesulfonyl)-4-methylvalerohydrazide (Ro 327315), is a potent, orally active inhibitor of the TNFconvertase (TACE), an enzyme responsible for proteolytic(More)
Reclaimed water quality has largely focused on meeting standards in the treated effluent. While the focus is well placed, reclaimed water may change before it is used at dispersed locations. Reclaimed water is a perishable product with a shelf life requiring packaging (i.e., piping) and preserving (with a disinfectant) during storage to minimize(More)
D.S. Akerib, J. Alvaro-Dean, M.S. Armel–Funkhouser, M.J. Attisha, L. Baudis, 5 D.A. Bauer, J. Beaty, P.L. Brink, R. Bunker, S.P. Burke, B. Cabrera, D.O. Caldwell, D. Callahan, J.P. Castle, C.L. Chang, R. Choate, M.B. Crisler, P. Cushman, R. Dixon, M.R. Dragowsky, D.D. Driscoll, L. Duong, J. Emes, R. Ferril, J. Filippini, R.J. Gaitskell, M. Haldeman, D.(More)
Alzheimer disease and vascular dementia are the 2 most common forms of cognitive impairment in the elderly. For decades, each was considered a distinct disorder; recent results, however, show that they share many characteristics, including risk factors, neuropathology, and hemodynamics. This has led to a new conception that Alzheimer disease and vascular(More)
Deregulation has created new market pressures for innovation across many national infrastructures. This, in turn, creates complex interdependencies. For example, in previous years both the US and European energy markets relied upon vertical integration. The same companies that generated the power were also, typically, responsible for its transmission to(More)
Accidents at Flixborough, Seveso, Bhopal, Three Mile Island, Windscale and Chernobyl have led to increasing concern over the safety and reliability of control systems. Human factors specialists have responded to this concern and have proposed a number of techniques which support the operator of such applications. Unfortunately, this work has not been(More)