William T. Abraham

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BACKGROUND Previous studies have suggested that cardiac resynchronization achieved through atrial-synchronized biventricular pacing produces clinical benefits in patients with heart failure who have an intraventricular conduction delay. We conducted a double-blind trial to evaluate this therapeutic approach. METHODS Four hundred fifty-three patients with(More)
2005 WRITING COMMITTEE MEMBERS Sharon Ann Hunt, MD, FACC, FAHA, Chair; William T. Abraham, MD, FACC, FAHA; Marshall H. Chin, MD, MPH, FACP; Arthur M. Feldman, MD, PhD, FACC, FAHA; Gary S. Francis, MD, FACC, FAHA; Theodore G. Ganiats, MD; Mariell Jessup, MD, FACC, FAHA; Marvin A. Konstam, MD, FACC; Donna M. Mancini, MD; Keith Michl, MD, FACP; John A. Oates,(More)
BACKGROUND Data from single-center studies suggest that echocardiographic parameters of mechanical dyssynchrony may improve patient selection for cardiac resynchronization therapy (CRT). In a prospective, multicenter setting, the Predictors of Response to CRT (PROSPECT) study tested the performance of these parameters to predict CRT response. METHODS AND(More)
Virend K. Somers, MD, DPhil, FAHA, FACC, Chair; David P. White, MD, Co-Chair; Raouf Amin, MD, Co-Chair; William T. Abraham, MD, FAHA, FACC; Fernando Costa, MD, FAHA; Antonio Culebras, MD, FAHA; Stephen Daniels, MD, PhD, FAHA; John S. Floras, MD, DPhil, FAHA, FACC; Carl E. Hunt, MD; Lyle J. Olson, MD, FACC; Thomas G. Pickering, MD, DPhil, FAHA; Richard(More)
BACKGROUND B-type natriuretic peptide is released from the cardiac ventricles in response to increased wall tension. METHODS We conducted a prospective study of 1586 patients who came to the emergency department with acute dyspnea and whose B-type natriuretic peptide was measured with a bedside assay. The clinical diagnosis of congestive heart failure was(More)
CONTEXT Cardiac resynchronization therapy (CRT) through biventricular pacing is an effective treatment for heart failure (HF) with a wide QRS; however, the outcomes of patients requiring CRT and implantable cardioverter defibrillator (ICD) therapy are unknown. OBJECTIVE To examine the efficacy and safety of combined CRT and ICD therapy in patients with(More)
BACKGROUND The ADHERE is designed to study characteristics, management, and outcomes in a broad sample of patients hospitalized with acute decompensated heart failure. Heart failure is a leading cause of hospitalization for adults older than 65 years in the United States. Most available data on these patients are limited by patient selection criteria and(More)
Mariell Jessup, MD, FACC, FAHA, Chair*; William T. Abraham, MD, FACC, FAHA†; Donald E. Casey, MD, MPH, MBA‡; Arthur M. Feldman, MD, PhD, FACC, FAHA§; Gary S. Francis, MD, FACC, FAHA§; Theodore G. Ganiats, MD ; Marvin A. Konstam, MD, FACC¶; Donna M. Mancini, MD#; Peter S. Rahko, MD, FACC, FAHA†; Marc A. Silver, MD, FACC, FAHA**; Lynne Warner Stevenson, MD,(More)
OBJECTIVES We sought to determine the effects of cardiac resynchronization therapy (CRT) in New York Heart Association (NYHA) functional class II heart failure (HF) and NYHA functional class I (American College of Cardiology/American Heart Association stage C) patients with previous HF symptoms. BACKGROUND Cardiac resynchronization therapy improves left(More)